Glutaraldehyde-fixed parietal peritoneum graft conduit to replace completely the portal vein during pancreaticoduodenectomy: A case report

Abstract

Highlights Pancreatic ductal adenocarcinoma often displays major vascular invasion. Portal vein and superior mesenteric artery resection can be performed safely. Venous end-to-end anastomosis is not always feasible during pancreaticoduodenectomy. Directly available peritoneum graft conduit doesn’t require anticoagulation. Glutaraldehyde solidifies and improves handling of peritoneum graft conduit.

Effect of Peritoneum Graft on Intestinal Anastomosis Healing After Deserosalization in Dogs

“…The Bp value among the peritoneal graft-coated group and control group at 15 th days post-operation was significantly different, which indicates that the coating of the injured site of the anastomosis with peritoneal graft increased the strength of the anastomotic site. These results are in agreement with others who reported a significant increase in strength and Bp of the anastomotic area after reinforcing with tissue graft [28,34,35]. However, there were differences in Bp between the 7 th and 15 th days groups but this difference was not significant.…”

“…However, there were differences in Bp between the 7 th and 15 th days groups but this difference was not significant. Ditek, et al have suggested that in the early phase of the healing period, the bursting pressure of the anastomotic area normally decreases because it depends on the inflammation rate and then increases as the strength holding capacity for suture material increases due to increases in the collage synthesis [35].…”