Glutaminolysis regulates endometrial fibrosis in intrauterine adhesion via modulating mitochondrial function
Pei Chen,
Chaoshuang Ye,
Yunke Huang
et al.
Abstract:Background
Endometrial fibrosis, a significant characteristic of intrauterine adhesion (IUA), is caused by the excessive differentiation and activation of endometrial stromal cells (ESCs). Glutaminolysis is the metabolic process of glutamine (Gln), which has been implicated in multiple types of organ fibrosis. So far, little is known about whether glutaminolysis plays a role in endometrial fibrosis.
Methods
The activation model of ESCs was construc… Show more
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