Glutamic acid production in an airlift reactor with net draft tube

Abstract

Abstract. Cultivation of Brevibacterium divaricatum for glutamic acid production in an airlift reactor with net draft tube was developed. Cell concentration gave an index for adding penicillin G. On-line estimation of total sugar concentration yielded an identified model which was used for determination of the substrate addition. Fermentation for glutamic acid production requires high oxygen concentration in the broth. The proposed reactor has the capability to provide sufficient oxygen for the fermentation. Since the reactor is suitable for fed-batch culture, the cultivation of B. divaricatum for glutamic acid production in the proposed reactor is successfully carried out.

An airlift reactor with double net draft tubes and its application in fermentation

“…Chisti et al [9] applied static mixers in the riser for redispersion of bubbles. Wu et al [10] proposed an airlift reactor with a net draft tube to enhance the volumetric oxygen transfer coefficient and applied to fermentation for yeast production [11] and glutamic acid production [12].…”