Glucose Oxidase–graphene–chitosan modified electrode for direct electrochemistry and glucose sensing

Kang, Xinhuang; Wang, Jun; Wang, Hong; Aksay, İlhan A.; Li, Jun; Lin, Yuehe

doi:10.1016/j.bios.2009.09.004

Cited by 1,157 publications

(534 citation statements)

References 52 publications

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“…Graphene paper electrodes have been used in lithium batteries, 17 and graphene oxide has been incorporated into a glucose biosensor. 18 Recently, Qu et al 19 used nitrogen-doped graphene, produced using chemical vapour deposition, to promote oxygen reduction in fuel cells.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical ascorbic acid sensor based on DMF-exfoliated graphene

et al. 2010

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This paper describes the electron transfer properties of graphene nano-sheets (GNSs) immobilised on pyrolysed photoresist film (PPF) electrodes. The former are produced by the dispersion and exfoliation of graphite in dimethylformamide, and they are characterised using transmission electron microscopy, scanning electron microscopy and Raman spectroscopy. Cyclic voltammetry and electrochemical impedance spectroscopy are used to quantify the effect of the GNSs on electrochemical surface area and on electron transfer kinetics. Compelling evidence is reported in relation to the importance of edgeplane sites and defects in the promotion of electron transfer at carbon nanostructures. A novel ascorbic acid (vitamin C) sensor is presented based on the PPF/GNS system, which is effective in the range 0.4 to 6.0 mM, with a 0.12 mM detection limit. The selectivity of the sensor is demonstrated using a commercially available vitamin C supplement. This is the first report of the electrochemical properties of graphene nano-sheets produced using liquid-phase exfoliation, and it will serve as an important benchmark in the development of inexpensive graphene-based electrodes with high surface area and electro-catalytic activity.

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Section: Introductionmentioning

confidence: 99%

Electrochemical ascorbic acid sensor based on DMF-exfoliated graphene

et al. 2010

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“…Furthermore, the analytical performance of the fabricated immunoelectrode has been compared with that of various recent immunosensors based on existing literature [38][39][40][41][42][43][44][45][46][47][48][49], as shown in Table 1. The present immunoelectrode displayed a good performance with considerable specificity and low detection of analytic concentration.…”

Section: Application Of the Immunoelectrode In Htert Spiked Sputum Samentioning

confidence: 99%

Graphene Oxide based Label Free Ultrasensitive Immunosensor for Lung Cancer Biomarker, hTERT

Choudhary¹

2013

J Biosens Bioelectron

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Significance of ResearchUnavailability of apposite diagnostic test capable of monitoring early stage progression/relapse of lung cancer is related to its high mortality rate wordwide. We report for the first time detection of lung cancer biomarker hTERT (human telomerase reverse transcriptase), using anti-hTERT for fabrication of graphene oxide (a low cost unique multifunctional material) based immunosensor in spiked sputum samples in the dynamic detection range of 100 fg mL -1 -10 ng mL -1 in 30 s exposure time. The easy fabrication of above said electrochemical immunosensor warrants the development of low cost and non invasive diagnostics (first and second stages) for lung cancer.

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“…Glutamate is an important neurotransmitter usually associated with brain damages [8] while ATP has been very recently associated to regulation of adaptive immune responses [9]. Several nano-materials have been proposed to improve devices performance including conductive polymers [10], nano-particles [11], graphene [12], and carbon nanotubes [13]. Recently, carbon nanotubes have been demonstrated to enhance the sensitivity for both exogenous [14] and endogenous [15] metabolites.…”

Section: Remote System For Monitoring Animal Modelsmentioning

confidence: 99%

Remote System for Monitoring Animal Models With Single-Metabolite Bio-Nano-Sensors

et al. 2013

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Abstract-A novel system for remote monitoring of metabolism in an animal model is proposed in this paper. The system is obtained by integrating bio-nano-sensors to detect singlemetabolites, an electrochemical front-end made with off-the-shelf components, a radio frequency communication sub-system, and an antenna of new design. The system has been calibrated and tested for continuous monitoring of four different metabolites: glucose, lactate, glutamate, and adenosine triphosphate. Tests using animal models (mice) have been conducted to investigate tissue inflammation induced by the implanted bio-nano-sensors. These tests confirm that our system is suitable and reliable for remote monitoring of single-metabolites in experiments with animal models.

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Glucose Oxidase–graphene–chitosan modified electrode for direct electrochemistry and glucose sensing

Cited by 1,157 publications

References 52 publications

Electrochemical ascorbic acid sensor based on DMF-exfoliated graphene

Electrochemical ascorbic acid sensor based on DMF-exfoliated graphene

Graphene Oxide based Label Free Ultrasensitive Immunosensor for Lung Cancer Biomarker, hTERT

Remote System for Monitoring Animal Models With Single-Metabolite Bio-Nano-Sensors

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