Glucose Biosensor Based on Pt Nanoparticles/Graphene Chitosan Bionanocomposites

Liu, Hui Ping; Zhan, Gong Yong; Dong, Qi; Lv, Yan; Wang, Jian Fang; Tao, Cheng; Hu, Zhi Hong

doi:10.4028/www.scientific.net/amm.328.695

Cited by 4 publications

(2 citation statements)

References 10 publications

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“…FTIR was used to verify the success of the reduction and the results are shown in Figure 2A. The peaks of GO-Nafion at 3300 cm −1 , 1729 cm −1 , 1624 cm −1 , and 1056 cm −1 represented the OH stretching vibration, C = O stretching vibration, C = C stretching vibration, and C-O symmetric vibration, respectively [34]. For the ERGO-Nafion after reduction, the peaks at 3300 cm −1 and 1729 cm −1 disappeared, and the C = C stretching vibration and C-O at 1624 cm −1 and 1056 cm −1 became weak, but did not completely disappear.…”

Section: Resultsmentioning

confidence: 99%

Construction of a Biosensor Based on a Combination of Cytochrome c, Graphene, and Gold Nanoparticles

Guo

Wang

Chen

et al. 2018

Sensors

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A biosensor based on a combination of cytochrome c (Cyt c), electrochemical reduced graphene oxides (ERGO), and gold nanoparticles (AuNPs) on a glassy carbon electrode (GCE) was fabricated. The proposed biosensor electrode was denoted as GCE/ERGO-Nafion/AuNPs/Cyt c/Nafion, where ERGO-Nafion was deposited by dropping graphene oxides-Nafion mixed droplet first and following electrochemical reduction, AuNPs were directly deposited on the surface of the ERGO-Nafion modified electrode by electrochemical reduction, and other components were deposited by the dropping-dry method. The effect of the deposition amount of AuNPs on direct electrochemistry of Cyt c in the proposed electrode was investigated. The hydrogen peroxide was taken to evaluate the performance of the proposed biosensor. The results showed that the biosensor has great analytical performance, including a high sensitivity, a wide linear range, a low detection limit, and good stability, reproducibility, and reliability.

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Section: Resultsmentioning

confidence: 99%

Construction of a Biosensor Based on a Combination of Cytochrome c, Graphene, and Gold Nanoparticles

Guo

Wang

Chen

et al. 2018

Sensors

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“…A thin film of chitosan containing graphene and gold nanoparticle has also been used to immobilize the glucose oxidase (GOx) enzyme [28,29]. A hybrid bionanocomposite consisting of GOx/Pt nanoparticles/graphene-chitosan has been reported to show a good amperometric response toward glucose sensing [30,31]. For a direct sensing mechanism (non-enzymatic process), some progress has been reported, such as in [32,33,34,35,36,37].…”

Section: Introductionmentioning

confidence: 99%

A Molecular Interaction Analysis Reveals the Possible Roles of Graphene Oxide in a Glucose Biosensor

et al. 2019

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In this paper, we report the molecular docking study of graphene oxide and glucose oxidase (GOx) enzyme for a potential glucose biosensing application. The large surface area and good electrical properties have made graphene oxide as one of the best candidates for an enzyme immobilizer and transducer in the biosensing system. Our molecular docking results revealed that graphene oxide plays a role as a GOx enzyme immobilizer in the glucose biosensor system since it can spontaneously bind with GOx at specific regions separated from the active sites of glucose and not interfering or blocking the glucose sensing by GOx in an enzyme-assisted biosensor system. The strongest binding affinity of GOx-graphene oxide interaction is −11.6 kCal/mol and dominated by hydrophobic interaction. Other modes of interactions with a lower binding affinity have shown the existence of some hydrogen bonds (H-bonds). A possibility of direct sensing (interaction) model of glucose by graphene oxide (non-enzymatic sensing mechanism) was also studied in this paper, and showed a possible direct glucose sensing by graphene oxide through the H-bond interaction, even though with a much lower binding affinity of −4.2 kCal/mol. It was also found that in a direct glucose sensing mechanism, the sensing interaction can take place anywhere on the graphene oxide surface with almost similar binding affinity.

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A review on chitosan and chitosan-based bionanocomposites: Promising material for combatting global issues and its applications

Azmana

Mahmood

Hilles

et al. 2021

International Journal of Biological Macromolecules

229

101

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Glucose Biosensor Based on Pt Nanoparticles/Graphene Chitosan Bionanocomposites

Cited by 4 publications

References 10 publications

Construction of a Biosensor Based on a Combination of Cytochrome c, Graphene, and Gold Nanoparticles

Construction of a Biosensor Based on a Combination of Cytochrome c, Graphene, and Gold Nanoparticles

A Molecular Interaction Analysis Reveals the Possible Roles of Graphene Oxide in a Glucose Biosensor

A review on chitosan and chitosan-based bionanocomposites: Promising material for combatting global issues and its applications

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