Glucose-6-phosphate Dehydrogenase

Löhr, G. W.; Waller, H. D.

doi:10.1016/b978-0-12-395630-9.50135-3

Cited by 87 publications

(53 citation statements)

References 10 publications

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“…The activities of G-6-PDH [19], 6-PGDH [20], NADP+-ICDH [21], and malic enzyme [22] were assayed by the respective spectrophotometric methods. The increase in extinction at 340 nm due to the formation of NADPH is regarded as the activity of the enzyme.…”

Section: Enzyme Assaysmentioning

confidence: 99%

Effects of Ethanol Treatment on Leydig Cellular NADPH-Generating Enzymes and Lipid Profiles.

1995

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Section: Enzyme Assaysmentioning

confidence: 99%

Effects of Ethanol Treatment on Leydig Cellular NADPH-Generating Enzymes and Lipid Profiles.

1995

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“…Testis was homogenized in 0.5 M Tris-HCl (pH 8.3) and centrifuged to estimate G-6-PDH (Lohr and Waller, 1974). Protein was estimated with folin phenol reagent and activity of enzymes was expressed in unit per mg of protein (Lowry et al, 1951).…”

Section: Biochemical Methodsmentioning

confidence: 99%

Effects of methanol extracts of Cuscuta reflexa Roxb. stem and Corchorus olitorius Linn. seed on male reproductive system of mice

Pal¹,

Gupta²,

Mazumder³

2009

Oriental Pharmacy and Experimental Medicine

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SUMMARYThe antifertility activity of methanol extract of Cuscuta reflexa Roxb. stem (MECR) and Corchorus olitorius Linn. seed (MECO) were studied on male Swiss albino mice. The extracts were found to decrease sperm count, percentage of motile sperm and testosterone level in treated mice when compared with vehicle control after 17 days of treatment. The weight of gonads, epididymis were decreased whereas no significant changes of the body weight of mice were observed after methanol extract treatments. The fertility test showed 100% negative result in MECR and MECO treated mice at medium and high dose level of treatment. MECR and MECO in low (25 mg/kg and 15 mg/kg, respectively), medium (50 mg/kg and 20 mg/kg, respectively) and high (75 mg/ kg and 25 mg/kg, respectively) dose level caused a simultaneous fall in testicular Δ5-3β-hydroxy steroid dehydrogenase and glucose-6-phosphate dehydrogenase activities which are involved in testicular steroidogenesis. Total cholesterol and ascorbic acid content in testis were increased significantly in gonads. The activities of lactate dehydrogenase, malic dehydrogenase and ascorbic acid oxidase were reduced whereas that of carbonic anhydrase was increased significantly in the testis of MECR and MECO treated mice. All these observations indicate that the methanol extract of C. reflexa stem and C. olitorius seed produced antifertility activity in sexually matured male mice, which may be due to inhibition of gonadal steroidogenesis. This activity may be attributed due to the presence of flavonoids and steroids, respectively.

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“…Oxidative enzymes like Succinate dehydrogenase (SDH), malate dehydrogenase (MDH) activity was estimated by the method of Nachlas et al (1960). Glucose-6-phosphate dehydrogenase (G6PDH) activity was assayed by the method of Lohr and Waller (1974). Glutamate dehydrogenase (GDH) was determined by the method of Lee and Lardy (1965).…”

Section: Analytical Proceduresmentioning

confidence: 99%

Modulation of Pimpinella tirupatiensis aqueous extract on Brain Mitochondrial Enzymes in STZ induced diabetic rats

Kumar¹,

Shanmugam²,

Ramakrishna³

et al. 2017

J App Pharm Sci

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The objective of the present study was to investigate the role of Pimpinella tirupatiensis (Pt) aqueous extract on brain mitochondrial enzymes in Streptozotocin (STZ) induced diabetic rats. Adult male wistar strain rats were divided into five groups as NC (normal control), Pt. (Pimpinella treatment), DC (Diabetic control), D+Pt (Diabetic+ Pimpinella treatment), D+Gli (Diabetic + Glibenclamide treatment). Treatment was given as per the experimental protocol for 30days. Succinate dehydrogenase (SDH), glucose-6-phosphate dehydrogenase (G6PD), malate dehydrogenase (MDH),and glutamate dehydrogenase (GDH), and lactae dehydrogenase (LDH) enzymes activities were assayed in the brain tissue. In diabetic rats, we observed decreased activities of SDH, G6PDH, MDH, GDH and increased LDH activity. However with the Pimpinella tirupatiensis treatment mitochondrial enzymes activities were came back to normalcy. Our results suggest that the Pt supplementation modulates the mitochondrial enzymes activities in diabetic rats.

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Glucose-6-phosphate Dehydrogenase

Cited by 87 publications

References 10 publications

Effects of Ethanol Treatment on Leydig Cellular NADPH-Generating Enzymes and Lipid Profiles.

Effects of Ethanol Treatment on Leydig Cellular NADPH-Generating Enzymes and Lipid Profiles.

Effects of methanol extracts of Cuscuta reflexa Roxb. stem and Corchorus olitorius Linn. seed on male reproductive system of mice

Modulation of Pimpinella tirupatiensis aqueous extract on Brain Mitochondrial Enzymes in STZ induced diabetic rats

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