Glucosamine and chondroitin for knee osteoarthritis: a double-blind randomised placebo-controlled clinical trial evaluating single and combination regimens

Fransen, Marlene; Agaliotis, Maria; Nairn, Lillias; Votrubec, M.; Bridgett, Lisa; Su, Steve; Jan, Stephen; March, Lyn; Edmonds, John; Norton, Robyn; Woodward, Mark; Day, Richard O.

doi:10.1136/annrheumdis-2013-203954

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Glukosamin2

Complementary Medicines1

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2024

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Cited by 177 publications

(146 citation statements)

References 35 publications

(32 reference statements)

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“…Eine Cochrane-Analyse von 2005, bei der 15 randomisierte klinische Studien (RCTs) ausgewertet wurden, weist eine signifikante Über-legenheit von Glukosamin gegenüber Placebo bei der Schmerzreduktion und bei der strukturellen Arthroseprogression (Gelenkspaltverschmälerung) über einen Zeitraum von 3 Jahren nach [46]. Entsprechende Ergebnisse wurden von einer neueren Studie auch für die Kombination von Glukosamin und Chondroitin nachgewiesen [21].…”

Section: Glukosaminunclassified

Supplements und Injektionen bei Arthrose und Knorpelschäden

Steinwachs¹,

Guhlke-Steinwachs²

2016

Arthroskopie

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Section: Glukosaminunclassified

Supplements und Injektionen bei Arthrose und Knorpelschäden

Steinwachs¹,

Guhlke-Steinwachs²

2016

Arthroskopie

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“…It is important in the biosynthesis of proteoglycan which is vital in maintaining cartilage integrity [7,8]. It is one of the most commonly used supplements in patients with OA at a recommended dose of 1.5 g daily.…”

Section: Glucosaminementioning

confidence: 99%

A Review of Nutraceuticals in Joint Arthritis

GEH¹

2015

J Pain Relief

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The use of nutraceuticals and supplements is common in the management of joint pathology. Due to this popularity, it is important that clinicians are aware of these therapies and have a basic understanding of them. Scientific studies examining the effects of nutraceuticals in joint arthritis are increasing. This short update aims to provide a commentary on the recent developments of these therapies commonly used in rheumatoid and osteoarthritis aiming to summarise their characteristics and efficacy.

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“…However, no statistical difference was found with individual treatment alone. 46 Fish oil use is gaining popularity for osteoarthritis. While there are some trials in rheumatoid arthritis, its use in osteoarthritis remains uncertain.…”

Section: Complementary Medicinesmentioning

confidence: 99%