The main goal of this Special Issue is to present the latest advances in research and novel applications of speech and language technologies based on the works presented at the IberSPEECH edition held in Barcelona in 2018, paying special attention to those focused on Iberian languages. IberSPEECH is the international conference of the Special Interest Group on Iberian Languages (SIG-IL) of the International Speech Communication Association (ISCA) and of the Spanish Thematic Network on Speech Technologies (Red Temática en Tecnologías del Habla, or RTTH for short). Several researchers were invited to extend their contributions presented at IberSPEECH2018 due to their interest and quality. As a result, this Special Issue is composed of 13 papers that cover different topics of investigation related to perception, speech analysis and enhancement, speaker verification and identification, speech production and synthesis, natural language processing, together with several applications and evaluation challenges.