Glottal Airflow Resistance in Excised Pig, Sheep, and Cow Larynges

Alipour, Fariborz; Jaiswal, Sanyukta

doi:10.1016/j.jvoice.2007.03.007

Cited by 45 publications

(37 citation statements)

References 21 publications

(18 reference statements)

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“…Briefly, the airflow increased significantly as the subglottal pressure increased. This result is consistent with the conclusions of Alipour et al 23,[38][39][40] and Jiang et al…”

Section: A Application To Different Hemilarynx Data Setssupporting

confidence: 93%

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Three-dimensional biomechanical properties of human vocal folds: Parameter optimization of a numerical model to match in vitro dynamics

Yang

Berry

Döllinger

2012

The Journal of the Acoustical Society of America

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The human voice signal originates from the vibrations of the two vocal folds within the larynx. The interactions of several intrinsic laryngeal muscles adduct and shape the vocal folds to facilitate vibration in response to airflow. Three-dimensional vocal fold dynamics are extracted from in vitro hemilarynx experiments and fitted by a numerical three-dimensional-multi-mass-model (3DM) using an optimization procedure. In this work, the 3DM dynamics are optimized over 24 experimental data sets to estimate biomechanical vocal fold properties during phonation. Accuracy of the optimization is verified by low normalized error (0.13 6 0.02), high correlation (83% 6 2%), and reproducible subglottal pressure values. The optimized, 3DM parameters yielded biomechanical variations in tissue properties along the vocal fold surface, including variations in both the local mass and stiffness of vocal folds. That is, both mass and stiffness increased along the superior-to-inferior direction. These variations were statistically analyzed under different experimental conditions (e.g., an increase in tension as a function of vocal fold elongation and an increase in stiffness and a decrease in mass as a function of glottal airflow). The study showed that physiologically relevant vocal fold tissue properties, which cannot be directly measured during in vivo human phonation, can be captured using this 3D-modeling technique.

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“…Briefly, the airflow increased significantly as the subglottal pressure increased. This result is consistent with the conclusions of Alipour et al 23,[38][39][40] and Jiang et al…”

Section: A Application To Different Hemilarynx Data Setssupporting

confidence: 93%

“…Finally, the application of the 3DM will also be used to evaluate the conclusions reported in other laryngeal tissue studies. 20,[23][24][25][26] Increased knowledge of the biomechanical parameters underlying laryngeal pathologies may facilitate clinical diagnosis of voice disorders, especially in the case of functional dysphonia.…”

mentioning

confidence: 99%

Three-dimensional biomechanical properties of human vocal folds: Parameter optimization of a numerical model to match in vitro dynamics

Yang

Berry

Döllinger

2012

The Journal of the Acoustical Society of America

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“…Amongst others, work has been carried out with a strong inclination towards fluid dynamics. This includes studies investigating (a) pressure-flow relationships (Alipour et al, 1997;Hottinger et al, 2007); (b) glottal resistance Alipour and Jaiswal, 2009) and glottal efficiency (Titze, 1988); (c) velocity fields within the glottis using particle imaging velocimetry (which in simple terms corresponds to turbulence analysis) ; (d) the dependency of f o on subglottal pressure (Solomon et al, 1994;Alipour and Scherer, 2007;Alipour and Jaiswal, 2008); and (e) the relationship between subglottal pressure and non-linear dynamics of laryngeal voice production (defining the phonation instability pressure, PIP) (Jiang and Titze, 1993;Jiang et al, 2003). Further research emphasis has been directed towards connecting vocal fold motion and geometry with the acoustic signal produced: this includes, amongst others, studies investigating (a) nonlinear dynamics in relation to glottal geometry (vocal fold adduction and/or elongation) (Berry et al, 1996;Jiang et al, 2003) and vocal fold asymmetry (Giovanni et al, 1999); (b) the importance of tissue properties on phonatory characteristics (Chan and Titze, 1999;Alipour et al, 2011); (c) mucosal wave propagation on the vocal folds (Kusuyama et al, 2001;Jiang et al, 2008); and (d) the mechanical forces applying on the vocal folds during phonation (Verdolini et al, 1998;Jiang et al, 2001b;Bakhshaee et al, 2013).…”

Section: Application Of Excised Larynx Experimentation To Human Voicementioning

confidence: 99%

Excised larynx experimentation: history, current developments, and prospects for bioacoustic research

Garcia

Herbst

2018

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The study of sound production mechanisms is a crucial, yet understudied, aspect of vocal communication research in vertebrates. In excised larynx experimentation (ELE), phonation is simulated ex vivo by forcing air through a larynx specimen mounted on a laboratory bench. The method provides unique insights into vocal production and allows inference of in vivo conditions. Here, we provide a historical overview of how this technique has been implemented, from antiquity to current state-of-theart setups. We review the advances made by applying ELE to human voice and biophysics research. We then highlight the promising research output resulting from ELE in animal bioacoustics, a research field that has largely overlooked the use of this method until very recently, but is now increasingly relying on this tool. We continue by discussing the limitations of ELE, depending on the focus of investigation. Finally, we suggest how this approach should be implemented and can be applied to various research questions. We conclude by underlining the value that ELE contributes to the comprehension of human voice as well as mammalian and avian vocal communication within an interdisciplinary approach.

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“…Various animal models have been used extensively in vocal fold studies with their results compared across models (Garrett, Coleman et al 2000;Jiang, Raviv et al 2001;Titze and Alipour 2006;Alipour and Jaiswal 2007;Alipour and Jaiswal 2008;Bless and Welham 2010;Alipour, Jaiswal et al 2011). Three of the more commonly used models in operative studies are rabbits (Thibeault, Gray et al 2002;Thibeault, Bless et al 2003;Branski, Rosen et al 2005;Carneiro and Scapini 2009;Campagnolo, Tsuji et al 2010), dogs (Garrett, Coleman et al 2000;Fleming, McGuff et al 2001;Rousseau, Hirano et al 2003;Karajanagi, Lopez-Guerra et al 2011) and pigs (Blakeslee, Banks et al 1995;Garrett, Coleman et al 2000;Jiang, Raviv et al 2001;Alipour and Jaiswal 2008;Fonseca, Malafaia et al 2010).…”

Section: Selection Of Animal Modelsmentioning

confidence: 99%