Glomus tumour of the male urethra: an unusual diagnostic

Abstract

A 56-year-old man was referred to a reconstructive urologist for evaluation of a tender nodule in the penoscrotal area. Penile Doppler ultrasound showed a non-compressible mass with internal vascularity within the corpora spongiosum, and MRI identified an enhancing, solid mass arising from the ventral aspect of the urethra. Surgical resection warranted partial excision and reconstruction of the urethra, which was achieved by a dorsal onlay buccal mucosal graft urethroplasty through a perineal incision with penile invagination. The histopathology report concluded to an invasive, high-grade urothelial carcinoma, for which an aggressive oncological approach was considered. However, discussion with the pathology team led to the identification of a glomus tumour for which the patient did not need additional procedures. Urethral glomus tumours are extremely rare and should be included in the differential diagnosis of urethral masses. This case exemplifies the importance of teamwork in the management of uncommon cases.

Malignant glomus tumor of prostate: A case report

“…The ectopic GTs have the same histological and immunohistochemical features as those in limbs; it is vital for the diagnosis of ectopic GTs (12). In immunohistochemistry of GTs, the marker for smooth muscle actin (a-SMA) and muscle-specific actin (MSA) are mostly positive, while the epithelial markers (e.g., CK5/6, CK7, CK20, and CKpan), CD56, CD34, CD31, and EMA are negative (9,(13)(14)(15).…”

Ischiadic Nerve Lesion Due to Metastasis of a Non-Differentiated Urethra Carcinoma: Case Report and Review of the Literature

“…As a complication of urethral carcinoma, a stricture of urethra can occur, and it can be proved using ultrasonography [17]. As an exceedingly rare entity, a glomus tumor of urethra in a male was described [18]. In veterinary medicine, urethral and low bladder carcinomas from transitional cell, were described in dogs (Canis lupus f. familiaris), followed by radiotherapy and in the cats (Felis silvestris f. catus) [19,20].…”

Primary Adrenal Glomus Tumor: The First Case Report

“…Vis-ceral organ occurrences have rarely been documented including the gastrointestinal tract, thoracic cavity, and gynecologic tract [1]. Reports of glomus tumors in the genitourinary tract are extremely rare and involve mostly in the penis, kidney, urinary bladder, renal pelvis, and urethra [3][4][5][6][7]. To our best knowledge, no cases of glomus tumor arising in the adrenal gland have been previously reported.…”