Glomerular hyperfiltration is a predictor of adverse outcomes following major urologic oncology surgery

Glomerular hyperfiltration is an independent predictor of postoperative outcomes: A NSQIPmulti‐specialty surgical cohort analysis

“…Although this association was not assessed in a multivariable analysis, Ui et al have previously demonstrated higher rates of bleeding among patients with GH undergoing surgery for gastrointestinal malignancies 13 . Finally, we found a high eGFR to be associated with prolonged length of stay, confirming the findings of a prior NSQIP study among patients with GH undergoing urologic surgeries 11 …”

“…13 Finally, we found a high eGFR to be associated with prolonged length of stay, confirming the findings of a prior NSQIP study among patients with GH undergoing urologic surgeries. 11 This study is not without limitations, however. First, it is retrospective in nature.…”

“…[6][7][8][9][10] Postoperatively, GH has been associated with adverse outcomes following total knee arthroplasty, and surgeries for gastrointestinal and urologic malignancies. [11][12][13] However, the effect of GH on postoperative outcomes has not been assessed more broadly and its importance in surgical patients has not been well established. Thus, we sought to assess the association between estimated glomerular filtration rate (eGFR) and postoperative outcomes using a multi-specialty surgical cohort containing over 1.6 million patients.…”

“…GH has been associated with metabolic risk, CVD and mortality and all‐cause mortality 6–10 . Postoperatively, GH has been associated with adverse outcomes following total knee arthroplasty, and surgeries for gastrointestinal and urologic malignancies 11–13 . However, the effect of GH on postoperative outcomes has not been assessed more broadly and its importance in surgical patients has not been well established.…”