Glomangioma of the Nasal Septum: A Case Report and Review

Chirilă, Magdalena; Rogojan, Liliana

doi:10.1177/014556131309200420

Cited by 16 publications

(19 citation statements)

References 9 publications

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“…Until now, so many various antibodies for immunohistochemical stains have been used for definitive diagnosis of sinonasal glomangiopericytoma. On the basis of17 patients' data (including our case) for immunohistochemical studies 1,4,5,[9][10][11][12][13][14][15][16][17][18][19][20] , various antibodies for immunohistochemical stains were used. Immunohistochemistry for vimentin, smooth muscle actin (SMA), muscle specific actin, CD34, desmin, S-100, cytokeratin including pankeratin, CD99, CD31, Bcl-2and Beta-Catenin was performed in at least 2 or more cases.…”

Section: Discussionmentioning

confidence: 99%

“…Except 4 patients whose treatment methods were not described in detail 6,7,10,20 , data on 16 patients (including our case) were collected for treatment modalities. 1,3,4,5,8,9,[11][12][13][14][15][16][17][18][19] The most common treatment modality was complete surgical excision through transnasal endoscopic surgery, used in 12 patients. The help of microdebrider and image-guided navigation system made it easier to remove the tumor completely in a few cases.…”

Section: Discussionmentioning

confidence: 99%

“…Except for two review articles, we thoroughly reviewed these articles (20 cases including our case) on the basis of age/sex, location, associated diseases, clinical symptoms, endoscopic findings, image findings, pathology, and treatment. 1,[3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]…”

Section: Search Strategy Of Literaturesmentioning

confidence: 99%

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Sinonasal Glomangiopericytoma: A Case Report and Literature Review

Min

Kim

2019

Bangladesh J Med Sci

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Glomangiopericytoma is a rare vascular tumor arising from the pericytes surrounding capillaries, and accounts for less than 0.5% of all sinonasal tumors. The aim of this study is to describe our recent experience of sinonasal glomangiopericytoma and thoroughly review our collected data on the basis of age/sex, location, associated diseases, clinical symptoms, endoscopic findings, image findings, pathology, and treatment. We found 21 articles (19 case reports and 2 review articles) relevant to our search since 2005. The mean age was 58.05 years, ranging from 19 years to 86 years with a female to male ratio of 3:1 (15:5). The most frequent site of origin was the nasal septum followed by the paranasal sinuses. The most common symptom was nasal obstruction, followed by epistaxis, headache, facial pain or pressure, and anosmia in decreasing order. Computed tomography was the most common imaging technique used to evaluate sinonasal glomangiopericytoma which the most common mentioned CT finding was soft tissue density mass with enhancement. The most common treatment modality was complete surgical excision through transnasal endoscopic surgery. Bangladesh Journal of Medical Science Vol.18(3) 2019 p.651-655

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Sinonasal Glomangiopericytoma: A Case Report and Literature Review

Min

Kim

2019

Bangladesh J Med Sci

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“…Radiologic investigation is essential in the workup for suspected sinonasal paragangliomas, especially for evaluation of possible extension into the skull base. CT scan was the most commonly used imaging modality in this review; however, MRI is considered to be the more specific because gadolinium injection allows for enhancement of the hypointense mass . Moreover, there are several cases where a “salt‐and‐pepper” appearance was described on MRI findings; this is very specific to sinonasal paragangliomas .…”

Section: Discussionmentioning

confidence: 99%

Characteristics and management of sinonasal paragangliomas: a systematic review

Nguyen

Patel

Arianpour

et al. 2018

Int Forum Allergy Rhinol

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Background: Paragangliomas of the nasal cavity and paranasal sinuses, although exceedingly rare, can exhibit frequent and aggressive recurrences. Our objective was to evaluate tumor characteristics, clinical course, management, and associated complications of sinonasal paragangliomas Methods: A systematic review of the literature was performed utilizing the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, searching for sinonasal paraganglioma. Studies meeting inclusion criteria were assessed for level of evidence. Patient demographics, tumor characteristics, primary intervention, and other clinical characteristics were evaluated.Results: Forty-five relevant studies encompassing 54 patients with sinonasal paraganglioma were identified. The most common tumor locations were the nasal cavity (66.7%), ethmoid sinuses (22.2%), maxillary sinuses (7.4%), and sphenoid sinuses (3.7%). Common presenting symptoms included recurrent epistaxis (68.5%), nasal obstruction (53.7%), and headache (13.0%). Tumors were malignant in 28.6% of patients. Only 4 cases (7.4%) involved functional tumors. Initial management was always surgical, via either an open (63.0%) or endoscopic (33.3%) approach. Radiotherapy was used as adjunctive treatment in 10 cases (18.5%). Recurrence rate was 21.7% and occurred between 12 to 156 months a er initial resection. The overall survival was 87.0% with a metastatic rate of 8.7%. Conclusion:Sinonasal paragangliomas are vascular neoplasms manifesting clinically with recurrent epistaxis and nasal obstruction. Management goals are total resection with clear margins and long-term follow-up due to tendency for local recurrence. Radiotherapy has been utilized as adjuvant therapy with variable results. Further randomized controlled studies may be invaluable in elucidating these findings. C 2018 ARS-AAOA, LLC.

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“…Because glomangiopericytoma, glomus tumor, and solitary fibrous tumor share characteristic ectatic branching vasculatures, they should be differentiated based on histologic and immunohistochemical findings. Glomus tumors and solitary fibrous tumors are less common than glomangiopericytoma in the sinonasal tract and are mainly the subject of case reports in the literature. Histologic findings of solitary fibrous tumors are quite different from those of glomangiopericytoma and glomus tumor.…”

Section: Discussionmentioning

confidence: 99%