apy such as statins, anti-platelet medication, and angiotensin converting enzyme inhibitors are prescribed less frequently in women than in men [4]. Increased prevalence of asymptomatic PAD in women and less consequent risk factor management may contribute to more advanced disease and higher percentage of critical limb ischaemia at the time of diagnosis. A large publication including 1,797,885 patients (56 % male) from the USA confi rmed that women with PAD are older and more likely to present with critical limb ischaemia [8]. In contrast, in the study by Rieß et al. critical limb ischaemia with peripheral lesions was found more often in men than in women.In comparison to women men had more often interventions below the knee. This might be explained by the higher percentage of men with critical limb ischaemia and diabetes. A current publication including 12,379 patients who underwent lover extremity intervention found no gender diff erence in intervention above or below the knee [9]. Periinterventional success rates and long-term outcome seem to be similar in men and women. But female sex was associated with a higher rate of vascular access side complications such as bleeding [9,10]. Similar results are reported by Rieß et al. with signifi cantly more bleeding complications requiring revision in women than in men. This might be explained by risk factors for local complications such as older age, smaller vessel size, more calcifi ed arteries and increased number of comorbidities. In addition, in the present manuscript the percentage of obesity was higher in women than in men.Women were rather discharged to rehabilitation and had longer in-hospital stays. This could be explained by the more advanced age and the higher comorbidities of women when treated with endovascular procedures. Moreover vascular complications prolong in-hospital stays. In addition, because of advanced age women are more likely to live alone and need external help after hospital discharge.It should be remarked that there remains a selection bias in the manuscript by Rieß et al. Naturally they could only report the data from patients presented to the hospital with already diagnosed symptomatic PAD. In clinical practise Although the infl uence of gender on atherosclerosis in general is well known, there is only little information about its impact on peripheral artery disease (PAD). In particular many trials on treatment of PAD include only a small number of women [1,2]. This leads to the false assumption that PAD is mainly a male disease. In addition, women are usually older when they suff er from atherosclerotic disease and have more comorbidities, which has important implications on their treatment [1,2].Therefore the paper by Rieß et al. about gender diff erences in endovascular treatment of PAD adds important contributions to the literature [3]. They report data from 2,798 endovascular procedures conducted between September and November 2015 at 74 vascular centres in Germany. In total 61 % of the patients were male and more than half of the ...