Abstract:In this paper, we formulate a virus infection model with n classes of target uninfected cells, n classes of latent infected cells, n classes of active infected cells, virus particles, and B cells. Three types of time delays and the impairment of B cells are involved. The Well-posedness of the model is demonstrated. Basic reproduction number of infection R 0 > 0 is established, which determines the existence of equilibria as follows; when R 0 is greater than unity, and then the model has two equilibria. Otherwi… Show more
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