GlObal Secondary Prevention strategiEs to Limit event recurrence after myocardial infarction: the GOSPEL study. A trial from the Italian Cardiac Rehabilitation Network: rationale and design

Abstract

The GOSPEL trial, the rationale and design of which we present here, was designed to test a new strategy of secondary prevention delivery and to raise standards of long-term secondary prevention in Italy. With a cohort of over 3200 patients, GOSPEL is the largest randomized, multifactorial lifestyle and risk factor intervention trial after myocardial infarction conducted so far.

Vascular risk factors for central retinal artery occlusion

“…3 It is known from the study of heart disease and stroke, that following the occurrence of a sentinel vascular event, the patient is more likely to develop subsequent vascular events. 4,5 Similarly, CRAO may also be the harbinger of a more serious vascular event. 6,7 The current management of CRAO is aimed at secondary prevention to prevent another ischemic event.…”

The Italian Survey on Cardiac Rehabilitation - 2008 (ISYDE-2008). Part 3. National availability and organization of cardiac rehabilitation facilities. Official report of the Italian Association for Cardiovascular Prevention, Rehabilitation and Epidemiolog

“…In fact in our survey 59% of patients admitted to CR are over 65 years of age and 25% are older than 75. Arguably, the high proportion of inpatient CR programs, mainly in regions with higher availability of cardiac surgery units, might be in answer to the need for a more efficient, comprehensive care process tailored to this growing, older and high-risk category of patients [20][21][22], who are frequently disabled, dependent and hampered by post-discharge organization and social deprivation problems.…”

A Ten Year Overview of Surgical and Interventional Arrhythmology in Russia. Service Peculiar Features in the Far East

“…упражнения, диета, устойчивость к психосоциальному стрессу и уменьшение массы тела) . Клинические конечные точки также были значительно сокращены: сердечно-сосудистая смертность, нефатальный инфаркт миокарда плюс инсульт на 33% (P = 0,02), кардиальная смерть плюс нефатальный инфаркт миокарда на 36% (P =0,02), все инсульты на 32% и вся смертность на 21% (P = не значительный) [565] .…”