Global research trends in tongue cancer from 2000 to 2022: bibliometric and visualized analysis

Wu, Beibei; Zhang, Tong; Dai, Ning; Luo, Ding; Wang, Xuejie; Qiao, Chen; Liu, Jian

doi:10.1007/s00784-024-05516-6

Cited by 1 publication

(1 citation statement)

References 62 publications

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“…Oral cancer remains a significant public health concern globally, with its incidence steadily rising in recent years [ 1 ]. Despite breakthroughs in treatment modalities such as surgery, chemotherapy, and radiotherapy, the long-term outlook for individuals with oral cancer remains poor, owing mostly to late-stage detection and the limited efficacy of available therapies against aggressive tumor morphologies [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Advancements in the Synthesis and Functionalization of Zinc Oxide-Based Nanomaterials for Enhanced Oral Cancer Therapy

Pei,

Natarajan,

Umapathy

et al. 2024

Molecules

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The fabrication of zinc oxide-based nanomaterials (including natural and synthetic polymers like sulfated polysaccharide, chitosan, and polymethyl methacrylate) has potential to improve oral cancer treatment strategies. This comprehensive review explores the diverse synthesis methods employed to fabricate zinc oxide nanomaterials tailored for oral cancer applications. Several synthesis processes, particularly sol–gel, hydrothermal, and chemical vapor deposition approaches, are thoroughly studied, highlighting their advantages and limitations. The review also examines how synthesis parameters, such as precursor selection, the reaction temperature, and growth conditions, influence both the physicochemical attributes and biological efficacy of the resulting nanomaterials. Furthermore, recent advancements in surface functionalization and modification strategies targeted at improving the targeting specificity and pharmaceutical effectiveness of zinc oxide-based nanomaterials in oral cancer therapy are elucidated. Additionally, the review provides insights into the existing issues and prospective views in the field, emphasizing the need for further research to optimize synthesis methodologies and elucidate the mechanisms underlying the efficacy of zinc oxide-based nanoparticles in oral cancer therapy.

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Section: Introductionmentioning

confidence: 99%