Global Research Trends in Dental Stem Cells: A Bibliometric and Visualized Study

Zhao, Hong; Liu, Jingbo; Bao, Zhi-Fan; Xu, Yingxin; Wang, Zhongqing

doi:10.1089/ten.teb.2021.0080

Cited by 20 publications

(14 citation statements)

References 17 publications

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“…The quantity and influence of research institutions is critical to the academic level of a country in a research field. 21 All of the top 15 most productive institutions were from developed countries, which implies an important role for economic foundation in supporting scientific research. Chiba University in Japan was the only Asian institution in the top 15 institutions for esketamine research, but it made the highest contribution to global research in terms of the total number of publications.…”

Section: Discussionmentioning

confidence: 99%

Global Trends and Hotspots in Esketamine Research: A Bibliometric Analysis of Past and Estimation of Future Trends

Li¹,

Peng²,

Liang³

et al. 2022

DDDT

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Background Being the S-enantiomer of racemic ketamine, esketamine is found to be effective for sedation, analgesia, and treating depression. However, there is no comprehensive bibliometric analysis about esketamine research. In this study, we aimed to determine the scientific output and emerging topics related to esketamine. Methods Esketamine-related articles and reviews that published between 2000 and 2020 were obtained from the Web of Science Core Collection database, using key word search of “esketamine” “esketamine hydrochloride”, “s-ketamine”, “S(+)-ketamine”, “(S)-ketamine”, or “(–)-ketamine”. Various bibliographic elements were collected, including the annual number of publications, citation frequency, countries/regions, institutions, authors, journals, and keywords. Two sorts of scientometric software, namely VOS viewer and CiteSpace, were used to conduct bibliometric and knowledge-map analyses. Results A total of 683 publications were included in the current study. We found the number of publications in esketamine research field had increased annually since 2016. The United States was the leader in this field, with the highest publications number (162, 23.72%), total citations (3504/9713, 36.08%) and H-index (40). The most productive institution was Chiba University in Japan, and esketamine-related papers were mainly published in the journal Anesthesia & Analgesia . The keyword co-occurrence analysis showed that keywords relevant to depression were the most frequent. Moreover, all identified keywords could be divided into four clusters, with the research focus gradually shifting from cluster of “anesthesia and analgesia detection” to “depression treatment effect.”. Conclusion The past two decades have shown a marked increase in esketamine research. The United States maintained a top position worldwide, making the most significant contributions in the field of esketamine research. The contributions and collaborations of Asian countries have continuously increased and is a strong area of growth as well as development in recent years. Additionally, the emerging hotspots of esketamine research concentrate on clarifying its depression treatment effect.

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Section: Discussionmentioning

confidence: 99%

Global Trends and Hotspots in Esketamine Research: A Bibliometric Analysis of Past and Estimation of Future Trends

Li¹,

Peng²,

Liang³

et al. 2022

DDDT

View full text Add to dashboard Cite

show abstract

“…Keyword co-occurrence analysis can be used to identify interests and hotspots in the field and to look for cutting-edge trends, aiding scientists to provide direction in a wide range ( Zhao et al, 2021 ). The frequency and total link strength results in the keyword analysis indicated that MSCs were the more researched cells, with research directed mainly towards the regeneration of NP cells, which is part of tissue engineering.…”

Section: Discussionmentioning

confidence: 99%

Global research status and hot trends in stem cells therapy for Intervertebral disc degeneration: A bibliometric and clinical study analysis

et al. 2022

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Background: Stem cells (SCs) therapy for intervertebral disc degeneration (IDD) has been studied for nearly 20 years and it is an important part of regenerative medicine and tissue engineering research, as well as a current research hotspot and challenge. Although the volume of literature has shown an annual growth trend, there is no literature available for bibliometric and clinical analysis of the content of multiple databases in this field.Methods: The articles were obtained from the WOSCC, Scopus, Pubmed, and ClinicalTrials on 27 December 2021. Three scientometric software (VOSviewer 1.6.17, CiteSpace 5.8.R.1 and Scimago Graphica) were used to perform bibliometric and knowledge-map analysis.Results: We included 867 articles from WOSCC, 716 articles from Scopus and 6 clinical studies from ClinicalTrials for literature analysis. Our results showed that China was the country with the highest number of publications, with the United States (US) being the leader in terms of international collaborations and the number of citations. Sakai D, Grad S and Hoyland JA had made outstanding contributions for their high productivity and the quality articles. Spine was the most published and most cited journal, in addition to Spine Journal and Biomaterials, which were also more authoritative journals and had received high citations. All of them had received high citations. Keyword co-occurrence studies suggested that the current hotspots were in mechanistic studies, including inflammation, apoptosis, exosome, autophagy, and others. Some studies had also investigated tissue-engineered scaffolds of SCs to better repair degenerated discs. Clinical studies were relatively scarce. Direct injection of Mesenchymal Stem Cells (MSCs) into degenerated discs for the treatment of Degenerative disc disease (DDD) was the current direction of research.Conclusion: This study demonstrates the global research hotspots, trends and clinical use of SCs in the treatment of IDD. It can help scholars to quickly understand the current status and hotspots of research in this field, and also provide some guidance and reference for those who are currently researching in this area.

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“…It is often used to analyze academic publications in a certain field to clarify overall trends in a field and assess the relative importance of academic achievements. Recently, bibliometric methods have been widely used in various research fields including Clinical Medicine [ 16 , 17 ], Biology [ 18 , 19 ], Sociology [ 20 , 21 ], Education [ 22 ], and Science and Engineering [ 23 , 24 ] and have played important roles in helping researchers quickly grasp research hotspots and trends in a specific field. The CiteSpace software was developed with Java programming language by Prof. Chaomei Chen of Drexel University [ 25 ].…”

Section: Introductionmentioning

confidence: 99%

Global Trends in Research of Mitochondrial Biogenesis over past 20 Years: A Bibliometric Analysis

Song

Liang

Wang

et al. 2023

Oxidative Medicine and Cellular Longevity

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Background. Mitochondrial biogenesis-related studies have increased rapidly within the last 20 years, whereas there has been no bibliometric analysis on this topic to reveal relevant progress and development trends. Objectives. In this study, a bibliometric approach was adopted to summarize and analyze the published literature in this field of mitochondrial biogenesis over the past 20 years to reveal the major countries/regions, institutions and authors, core literature and journal, research hotspots and frontiers in this field. Methods. The Web of Science Core Collection database was used for literature retrieval and dataset export. The CiteSpace and VOSviewer visual mapping software were used to explore research collaboration between countries/regions, institutions and authors, distribution of subject categories, core journals, research hotspots, and frontiers in this field. Results. In the last 20 years, the annual number of publications has shown an increasing trend yearly. The USA, China, and South Korea have achieved fruitful research results in this field, among which Duke University and Chinese Academy of Sciences are the main research institutions. Rick G Schnellmann, Claude A Piantadosi, and Hagir B Suliman are the top three authors in terms of number of publications, while RC Scarpulla, ZD Wu, and P Puigserver are the top three authors in terms of cocitation frequency. PLOS One, Biochemical and Biophysical Research Communications, and Journal of Biological Chemistry are the top three journals in terms of number of articles published. Three papers published by Richard C Scarpulla have advanced this field and are important literature for understanding the field. Mechanistic studies on mitochondrial biosynthesis have been a long-standing hot topic; the main keywords include skeletal muscle, oxidative stress, gene expression, activation, and nitric oxide, and autophagy and apoptosis have been important research directions in recent years. Conclusion. These results summarize the major research findings in the field of mitochondrial biogenesis over the past 20 years in various aspects, highlighting the major research hotspots and possible future research directions and helping researchers to quickly grasp the overview of the developments in this field.

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Global Research Trends in Dental Stem Cells: A Bibliometric and Visualized Study

Cited by 20 publications

References 17 publications

Global Trends and Hotspots in Esketamine Research: A Bibliometric Analysis of Past and Estimation of Future Trends

Global Trends and Hotspots in Esketamine Research: A Bibliometric Analysis of Past and Estimation of Future Trends

Global research status and hot trends in stem cells therapy for Intervertebral disc degeneration: A bibliometric and clinical study analysis

Global Trends in Research of Mitochondrial Biogenesis over past 20 Years: A Bibliometric Analysis

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