Global, regional, and national burden of Guillain–Barré syndrome and its underlying causes from 1990 to 2019

Bragazzi, Nicola Luigi; Kolahi, Ali‐Asghar; Nejadghaderi, Seyed Aria; Lochner, Piergiorgio; Brigo, Francesco; Naldi, Andrea; Lanteri, Paola; Garbarino, Sergio; Sullman, Mark J.M.; Dai, Hancheng; Wu, Jianhong; Kong, Jude Dzevela; Jahrami, Haitham; Sohrabi, Mohammad‐Reza; Safiri, Saeid

doi:10.1186/s12974-021-02319-4

Cited by 29 publications

(20 citation statements)

References 54 publications

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“…The Danish study found that the incidence was 44% higher in men, again mirroring our findings (2.0 vs. 1.4), and across the previous literature [44]. Finally, recent data from the Global Burden of Diseases Study in 2019 [52] found that the age-standardised prevalence of GBS had a small positive association with the level of socio-economic development, which mirrors the trends of higher incidence and lifetime prevalence we saw with lower levels of deprivation.…”

Section: Plos Onesupporting

confidence: 91%

Prevalence and incidence of neuromuscular conditions in the UK between 2000 and 2019: A retrospective study using primary care data

et al. 2021

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Background In the UK, large-scale electronic primary care datasets can provide up-to-date, accurate epidemiological information on rarer diseases, where specialist diagnoses from hospital discharges and clinic letters are generally well recorded and electronically searchable. Current estimates of the number of people living with neuromuscular disease (NMD) have largely been based on secondary care data sources and lacked direct denominators. Objective To estimate trends in the recording of neuromuscular disease in UK primary care between 2000–2019. Methods The Clinical Practice Research Datalink (CPRD) database was searched electronically to estimate incidence and prevalence rates (per 100,000) for a range of NMDs in each year. To compare trends over time, rates were age standardised to the most recent CPRD population (2019). Results Approximately 13 million patients were actively registered in each year. By 2019, 28,230 active patients had ever received a NMD diagnosis (223.6), which was higher among males (239.0) than females (208.3). The most common classifications were Guillain-Barre syndrome (40.1), myasthenia gravis (33.7), muscular dystrophy (29.5), Charcot-Marie-Tooth (29.5) and inflammatory myopathies (25.0). Since 2000, overall prevalence grew by 63%, with the largest increases seen at older ages (≥65-years). However, overall incidence remained constant, though myasthenia gravis incidence has risen steadily since 2008, while new cases of muscular dystrophy fell over the same period. Conclusions Lifetime recording of many NMDs on primary care records exceed current estimates of people living with these conditions; these are important data for health service and care planning. Temporal trends suggest this number is steadily increasing, and while this may partially be due to better recording, it cannot be simply explained by new cases, as incidence remained constant. The increase in prevalence among older ages suggests increases in life expectancy among those living with NMDs may have occurred.

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Section: Plos Onesupporting

confidence: 91%

Prevalence and incidence of neuromuscular conditions in the UK between 2000 and 2019: A retrospective study using primary care data

et al. 2021

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“…SDI is a composite indicator that measures the developmental level of each country. It is defined as 0 in the lowest case and 1 in the highest case, and it is calculated based on the lag-distributed income per capita, the total fertility rate for those younger than 25 years, and the average educational level of the population over the age of 15 years ( 18 ). In our study, the age-standardized prevalence and YLD for each region and YLD for each country were estimated according to the SDI.…”

Section: Methodsmentioning

confidence: 99%

“…Our dataset for neck pain between 1990 and 2019 was obtained from the GBD website using GBD standards. Several articles have already been published in various disease fields using GBD data (5,(16)(17)(18).…”

Section: Overviewmentioning

confidence: 99%

Global, regional, and national neck pain burden in the general population, 1990–2019: An analysis of the global burden of disease study 2019

Shin

Koyanagi

et al. 2022

Front. Neurol.

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BackgroundThis study describes the global epidemiology and trends associated with neck pain. Global Burden of Disease data collected between 1990 and 2019 were used to determine the global burden of neck pain in the general populations of 204 countries.MethodsGlobal, regional, and national burdens of neck pain determined by prevalence, incidence, and years lived with a disability (YLD) from 1990 to 2019 were comprehensively analyzed according to age, gender, and socio-demographic index using the Global Burden of Disease Study 1990 and 2019 data provided by the Institute for Health Metrics and Evaluation.ResultsGlobally, in 2019, the age-standardized rates for prevalence, incidence, and YLD of neck pain per 100,000 population was 2,696.5 (95% uncertainty interval [UI], 2,177.0 to 3,375.2), 579.1 (95% UI, 457.9 to 729.6), and 267.4 (95% UI, 175.5 to 383.5) per 100,000 population, respectively. Overall, there was no significant difference in prevalence, incidence, or YLD of neck pain between 1990 and 2019. The highest age-standardized YLD of neck pain per 100,000 population in 2019 was observed in high-income North America (479.1, 95% UI 323.0 to 677.6), Southeast Asia (416.1, 95% UI 273.7 to 596.5), and East Asia (356.4, 95% UI 233.2 to 513.2). High-income North America (17.0, 95% UI 9.0 to 25.4%) had the largest increases in YLD of neck pain per 100,000 population from 1990 to 2019. At the national level, the highest age-standardized YLD of neck pain was found in the Philippines (530.1, 95% UI 350.6 to 764.8) and the highest change age-standardized YLD between 1990 and 2019 was found in the United States (18.4, 95% UI 9.9 to 27.6%). Overall, the global burden of neck pain increased with age until the age of 70–74 years, and was higher in women than men. In general, positive associations between socio-demographic index and burden of neck pain were found.ConclusionsBecause neck pain is a major public health burden with a high prevalence, incidence, and YLD worldwide, it is important to update its epidemiological data and trends to cope with the future burden of neck pain.

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“…The SDI is a composite indicator that measures the development of individual countries. It is defined as 0 in the lowest case and 1 in the highest case and calculated based on the lag-distributed income per capita, the total fertility rate for those under 25, and the average educational level of the population over the age of 15 ( 17 ). In our study, the age-standardized prevalence and DALYs for each region and DALYs for each country were estimated according to the SDI.…”

Section: Methodsmentioning

confidence: 99%

The Global Burden of Motor Neuron Disease: An Analysis of the 2019 Global Burden of Disease Study

2022

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Up-to-date, accurate information on the disease burden of motor neuron disease (MND) is the cornerstone for evidence-based resource allocation and healthcare planning. We aimed to estimate the burden of MND globally from 1990 to 2019, as part of the Global Burden of Disease, Injuries and Risk Factor (GBD) study. Amyotrophic lateral sclerosis, progressive muscular atrophy, primary lateral sclerosis, pseudobulbar palsy, spinal muscular atrophy and hereditary spastic paraplegia- were included for analysis as MNDs. We measured age-standardized incidence, prevalence, death, and disability-adjusted life-years (DALYs) in 204 countries and territories worldwide from 1990 to 2019 using spatial Bayesian analyses. The effects of age, sex, and the sociodemographic index (measures of income per capita, education, and fertility) on incidence, prevalence, death, and disability-adjusted life-years due to MNDs were explored. According to 2019 GBD estimates, there were ~268,673 [95% uncertainty interval (UI), 213,893–310,663] prevalent cases and 63,700 (95% UI, 57,295–71,343) incident cases of MND worldwide. In 2019, MND caused 1,034,606 (95% UI, 979,910–1,085,401) DALYs and 39,081 (95% UI, 36,566–41,129) deaths worldwide. The age-standardized rates of prevalence, incidence, death, and DALYs for MNDs in 2019 were 3.37 (95% UI, 2.9–3.87) per 100,000 people, 0.79 (95% UI, 0.72–0.88) per 100,000 people, 0.48 (95% UI, 0.45–0.51) per 100,000 people, and 12.66 (95% UI, 11.98–13.29) per 100,000 people, respectively. The global prevalence and deaths due to MND in 2019 were increased (1.91% [95% UI, 0.61–3.42] and 12.39% [95% UI, 5.81–19.27], respectively) compared to 1990, without significant change in incidence. More than half of the prevalence and deaths due to MND occurred in three high-income regions (North America, Western Europe, and Australasia). In most cases, the prevalence, incidence, and DALYs of MNDs were high in regions with high sociodemographic index; however, in high-income East Asia, these were relatively low compared to similar sociodemographic index groups elsewhere. The burden of MND increased between 1990 and 2019. Its expected increase in the future highlights the importance of global and national healthcare planning using more objective evidence. Geographical heterogeneity in the MND burden might suggest the influences of sociodemographic status and genetic background in various regions.

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Global, regional, and national burden of Guillain–Barré syndrome and its underlying causes from 1990 to 2019

Cited by 29 publications

References 54 publications

Prevalence and incidence of neuromuscular conditions in the UK between 2000 and 2019: A retrospective study using primary care data

Prevalence and incidence of neuromuscular conditions in the UK between 2000 and 2019: A retrospective study using primary care data

Global, regional, and national neck pain burden in the general population, 1990–2019: An analysis of the global burden of disease study 2019

The Global Burden of Motor Neuron Disease: An Analysis of the 2019 Global Burden of Disease Study

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