Global, regional, and national burden of HIV and other sexually transmitted infections in older adults aged 60–89 years from 1990 to 2019: results from the Global Burden of Disease Study 2019

Fu, Leiwen; Tian, Tian; Wang, Bingyi; Lu, Zhen; Bian, Junye; Zhang, Weijie; Wu, Xinsheng; Li, Xinyi; Siow, Richard C; Fang, Evandro Fei; He, Na; Zou, Huachun

doi:10.1016/s2666-7568(23)00214-3

Cited by 6 publications

(1 citation statement)

References 29 publications

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“…Also considering the other continents, the highest incidence rate of syphilis from 1990 to 2019 occurred in central Sub-Saharan Africa (10·2 per 100,000 population) [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Atypical Manifestations of Syphilis: A 10-Year Retrospective Study

Ciccarese,

Facciorusso,

Mastrolonardo

et al. 2024

JCM

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Background: The incidence of syphilis has increased in high-income countries in the past few decades, especially among men who have sex with men. In the present study, we aimed to analyze the correlations between atypical syphilis manifestations and the demographic, clinical, and laboratory features of patients and to review unusual presentations of syphilis reported in the literature. Methods: We conducted a retrospective analysis of 307 patients with syphilis diagnosed between 1 January 2013 and 31 October 2023 at the sexually transmitted infection (STI) centers of the University of Genoa and University of Foggia with both typical and atypical manifestations of disease. Results: In our series, atypical manifestations were detected in 25.8% of the patients, especially in the secondary stage of the disease. Lesions with annular morphology and lesions presenting as itchy erythematous scaly plaques with a psoriasiform appearance were the most common atypical presentations of secondary syphilis. A statistical analysis revealed that homosexual orientation, syphilis reinfection, and venereal disease research laboratory (VDRL) titers > 1:32 were correlated with atypical manifestations. Conclusions: Our study demonstrates that the spectrum of syphilis manifestations, in all the stages of the disease, is wide; atypical manifestations often pose diagnostic challenges, may delay the provision of appropriate treatment, and facilitate the spread of the infection.

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“…Also considering the other continents, the highest incidence rate of syphilis from 1990 to 2019 occurred in central Sub-Saharan Africa (10·2 per 100,000 population) [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Atypical Manifestations of Syphilis: A 10-Year Retrospective Study

Ciccarese,

Facciorusso,

Mastrolonardo

et al. 2024

JCM

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HIV and other sexually transmitted infections in older adults

Karaye,

Kyriacou

2024

The Lancet Healthy Longevity

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Trend and driving factors in burden of age-related macular degeneration in older adults aged 60–89 years: a global analysis over three decades

Ni,

Wu,

Zha

et al. 2024

Age and Ageing

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Background To explore temporal trends and determine driving factors of age-related macular degeneration (AMD) burden in older adults aged 60–89 years at global, regional and national levels from 1990 to 2019. Methods Prevalence and years lived with disability (YLDs) were extracted. Joinpoint regression analysis was adopted to calculate average annual percentage change and to identify the year with the most significant changes. Global trends were stratified by sex, age and sociodemographic index, and regional and national trends were explored. Decomposition analysis was conducted to determine what extent the forces of population size, age structure and epidemiologic change driving alterations of AMD burden. Results Globally, prevalence rate slightly increased whereas YLDs rate decreased. The year 2005 marked a turning point where both prevalence and YLDs started to decline. Regionally, Western Sub-Saharan Africa had the highest prevalence and YLDs rates in 2019, with East Asia experiencing the most notable rise in prevalence from 1990 to 2019. Global decomposition revealed that the increased case number was primarily driven by population growth and ageing, and epidemiological change was only detected to lessen but far from offset these impacts. Conclusions Although there was only slight increase or even decrease in prevalence and YLDs rates of AMD in older adults, the case number still nearly doubled, which may be primarily attributed to population growth and ageing, coupled with the emerging growing pattern of prevalence rate from 2015, collectively suggesting a huge challenge in control and management of AMD.

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Global, regional, and national burden of HIV and other sexually transmitted infections in older adults aged 60–89 years from 1990 to 2019: results from the Global Burden of Disease Study 2019

Cited by 6 publications

References 29 publications

Atypical Manifestations of Syphilis: A 10-Year Retrospective Study

Atypical Manifestations of Syphilis: A 10-Year Retrospective Study

HIV and other sexually transmitted infections in older adults

Trend and driving factors in burden of age-related macular degeneration in older adults aged 60–89 years: a global analysis over three decades

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