Global prevalence of cerebral palsy: A systematic analysis

Abstract

Aim: To determine trends and current estimates in regional and global prevalence of cerebral palsy (CP).Method: A systematic analysis of data from participating CP registers/surveillance systems and population-based prevalence studies (from birth year 1995) was performed. Quality and risk of bias were assessed for both data sources. Analyses were conducted for pre-/perinatal, postnatal, neonatal, and overall CP. For each region, trends were statistically classified as increasing, decreasing, heterogeneous, or no change, and most recent prevalence estimates with 95% confidence intervals (CI) were calculated. Meta-analyses were conducted to determine current birth prevalence estimates (from birth year 2010).Results: Forty-one regions from 27 countries across five continents were represented. Pre-/perinatal birth prevalence declined significantly across Europe and Australia (11 out of 14 regions), with no change in postneonatal CP. From the limited but increasing data available from regions in low-and middle-income countries (LMICs), birth prevalence for pre-/perinatal CP was as high as 3.4 per 1000 (95% CI 3.0-3.9) live births. Following meta-analyses, birth prevalence for pre-/perinatal CP in regions from high-income countries (HICs) was 1.5 per 1000 (95% CI 1.4-1.6) live births, and 1.6 per 1000 (95% CI 1.5-1.7) live births when postneonatal CP was included.

DMCN 2022 highlights: Applying global perspectives to paediatric disability research

“…This past year, we have placed increasing emphasis on a global perspective, encouraging diversity in inviting reviewers and commentary authors, and encouraging international research, with better documentation of clinical features, experience, and epidemiology, including a landmark paper on global CP prevalence. 5 We also devoted more attention to languages other than English. With help from authors and societies, we have published excellent translations of abstracts, manuscripts, and podcasts into the languages of their varied communities (https://www.macke ith.co.uk/journ al/ trans lated -mater ial/).…”

“…This past year, we have placed increasing emphasis on a global perspective, encouraging diversity in inviting reviewers and commentary authors, and encouraging international research, with better documentation of clinical features, experience, and epidemiology, including a landmark paper on global CP prevalence 5 . We also devoted more attention to languages other than English.…”

Respiratory Health Inequities among Children and Young Adults with Cerebral Palsy in Aotearoa New Zealand: A Data Linkage Study

“…Cerebral palsy (CP) is the most common childhood physical disability in high income countries, with a prevalence between 1.4 and 2.1 cases per 1000 live births [ 1 ]. Respiratory-related illness in CP is the most common cause of mortality, morbidity, and poor quality of life, especially for those living with greater disability [≈26% of the CP population is classified as combined Gross Motor Function Classification System (GMFCS) IV and V] [ 2 , 3 ].…”

The Greek Version of Mini-Manual Ability Classification System (Mini-MACS): Translation and Reliability Study

“…Cerebral palsy (CP) is the most common cause of childhood physical disability with 17 million people with CP worldwide, which leads to fine and gross motor impairments and activities limitations [1]. The current overall CP birth prevalence in high-income regions of Australia and Europe, including Greece, is 1.6 per 1000 live births [2], observing a drop by 25% compared to 2013 (2.1 per 1000) [3]. More than 50% of children with CP have manual ability problems [4].…”