Global prevalence of aggressive periodontitis: A systematic review and meta‐analysis

Abstract

Aim The prevalence of aggressive periodontitis (AgP) varies considerably between studies. The aim of this meta‐analysis was to estimate, throughout the world, the prevalence of this disease. Materials and Methods Pubmed/Medline, Scopus, Science Direct, EBSCO and Cochrane library were systematically searched up to March 2018. Study selection criteria included cross‐sectional studies reporting prevalence of AgP in non‐specific population and permanent dentition. We assessed risk of bias using the Joanna Briggs Institute tool. A random effect meta‐analysis model was used to estimate the prevalence of AgP. Publication bias was assessed by Begg and Egger's tests and visual aspect of funnel plot. Results A total of 33 articles were included. Pooled prevalence for AgP was 1.6% (95% CI 1.1–2.3). Higher pooled prevalence rates were reported in Africa (4.2%, 95% CI 2.0–7.1) and South America (4.0%, 95% CI 0.9–9.1) compared with Europe (0.1%, 95% CI 0.1–0.2). A pooled prevalence of 1.2%, 95% CI 0.5–2.2 was found in Asia and 0.8%, 95% CI 0.4–1.4 in North America. Heterogeneity between groups was statistically significant (Q statistic p < .001). Conclusions A relatively high prevalence of AgP was found in Africa. However, the data support the weakness of the definition of this form of periodontal disease. Studies with less heterogeneity are needed to address accurately the prevalence of AgP.

Association between periodontitis and the Mediterranean diet in young Moroccan individuals

“…As indicated above, we focused on a specific type of periodontitis formerly recognized as AgP because this disease form has been studied for a long time 6,21 and is highly prevalent in young Moroccan individuals 2‐4,6 . The 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions introduced a new periodontitis classification scheme 22 in which chronic periodontitis (CP) and AgP are now grouped under a single category, periodontitis.…”

“…Studies have demonstrated a geographic variation in the prevalence of periodontitis in children and young adults, with a high prevalence in Africa and in populations of African descent 1‐6 . An epidemiologic study conducted in Morocco, North Africa, 4 reported that periodontitis affected 4.9% of individuals aged 12‐25 years.…”

“…In addition to the early age of onset, periodontitis in these studies showed unique phenotypes such as the initial involvement of a single or few teeth (molar/incisor pattern) and rapid disease progression, 1‐3 which was formerly known as aggressive periodontitis (AgP) 7 . It causes rapid destruction of the periodontal tissues and ultimately leads to early tooth loss, 1,6 which may have a significant negative impact on the quality of life 8 …”

Orthodontic treatment of an adult patient with aggressive periodontitis – A case report

“…The prevalence of aggressive periodontitis varies significantly between populations and different racial/ethnic origins (Susin et al, 2014). The pool prevalence of aggressive periodontitis was 1.6% and relatively higher prevalence was found in Africa (4.2%) (Bouziane et al, 2020). In a small population study in Malaysia, the prevalence of aggressive periodontitis was 5.3% (Yee et al, 2016).…”

Analysis of biochemical markers in the saliva and correlation with clinical parameters in patients with aggressive periodontitis, before and after the therapy

“…Destruction of the periodontal tissue begins in the area of the first molars and incisors, and with aging it can involve the periodontium of adjacent teeth. It affects the peridontal tissue of at least three permanent teeth, except the first molars and incisors [1].…”