Global patterns of human mitochondrial DNA and Y-chromosome structure are not influenced by higher migration rates of females versus males

Wilder, Jason A.; Kingan, Sarah B.; Mobasher, Zahra; Pilkington, Maya Metni; Hammer, Michael F.

doi:10.1038/ng1428

Cited by 132 publications

(138 citation statements)

References 22 publications

Supporting

Mentioning

127

Contrasting

Unclassified

Order By: Relevance

“…Given the diversity of social and mating systems among human populations (42) and the many factors controlling postmarital residence choice in tribal groups (43, 44), we would not generalize our results to other ethnic groups and other regions of the world. Moreover, it is still unclear how local patterns of sex-bias dispersal may affect genetic structure at a larger continental scale (11). However, we show here that accurate information on social organization and sex-specific dispersal can be retrieved from genetic data alone.…”

Section: Resultsmentioning

confidence: 68%

“…Several studies have shown that women could move among populations at higher rates than men (5)(6)(7)(8), potentially explaining lower levels of local differentiation for mtDNA than Y chromosome markers (e.g., 9, 10), even though a recent analysis revealed similar levels of genetic structure at a broader scale (11). Different forms of social organization can impact patterns and levels of genetic diversity (12,13), and sex differences in postmarital residence choice have been proposed to greatly affect isolation by distance patterns in humans (6).…”

mentioning

confidence: 99%

See 1 more Smart Citation

Molecular analysis reveals tighter social regulation of immigration in patrilocal populations than in matrilocal populations

Hamilton

Stoneking

Excoffier³

2005

Proc. Natl. Acad. Sci. U.S.A.

103

View full text Add to dashboard Cite

Human social organization can deeply affect levels of genetic diversity. This fact implies that genetic information can be used to study social structures, which is the basis of ethnogenetics. Recently, methods have been developed to extract this information from genetic data gathered from subdivided populations that have gone through recent spatial expansions, which is typical of most human populations. Here, we perform a Bayesian analysis of mitochondrial and Y chromosome diversity in three matrilocal and three patrilocal groups from northern Thailand to infer the number of males and females arriving in these populations each generation and to estimate the age of their range expansion. We find that the number of male immigrants is 8 times smaller in patrilocal populations than in matrilocal populations, whereas women move 2.5 times more in patrilocal populations than in matrilocal populations. In addition to providing genetic quantification of sex-specific dispersal rates in human populations, we show that although men and women are exchanged at a similar rate between matrilocal populations, there are far fewer men than women moving into patrilocal populations. This finding is compatible with the hypothesis that men are strictly controlling male immigration and promoting female immigration in patrilocal populations and that immigration is much less regulated in matrilocal populations.ethnogenetics ͉ human evolution ͉ sex-bias dispersal G enetic analyses have supported the existence of sex-biased gene flow in various human populations (1-4). Several studies have shown that women could move among populations at higher rates than men (5-8), potentially explaining lower levels of local differentiation for mtDNA than Y chromosome markers (e.g., 9, 10), even though a recent analysis revealed similar levels of genetic structure at a broader scale (11). Different forms of social organization can impact patterns and levels of genetic diversity (12, 13), and sex differences in postmarital residence choice have been proposed to greatly affect isolation by distance patterns in humans (6). The patterns of gender-specific genetic markers, such as mitochondrial and Y chromosome diversity, were recently found to be deeply affected by postmarital residence choice in six populations of northern Thailand (14). Patrilocal populations, where men remain in their natal village and women move to their husband's village, showed lower levels of Y chromosome diversity than matrilocal populations; the reverse situation was observed for mtDNA diversity. Moreover, genetic distances were found to be lower for mtDNA between patrilocal populations than between matrilocal populations, a situation that was reversed for Y chromosome markers (14). Although these results strongly supported the view that sex-biased dispersal shaped patterns of diversity within and between populations, no attempt was made to quantify and compare the movement of males and females in the two types of societies. Such quantitation may yield additional insights into cult...

show abstract

Section: Resultsmentioning

confidence: 68%

mentioning

confidence: 99%

Molecular analysis reveals tighter social regulation of immigration in patrilocal populations than in matrilocal populations

Hamilton

Stoneking

Excoffier³

2005

Proc. Natl. Acad. Sci. U.S.A.

103

View full text Add to dashboard Cite

show abstract

“…It is important to note that different mutation rates, as well as methods used to assay variation, on the NRY and mtDNA may contribute to some of the contrasting patterns observed here. 46 Future studies that examine Y chromosome and mitochondrial DNA sequence variation in the same samples representing African geographic and linguistic diversity will help to further elucidate the effects of Bantu expansions on the complex genetic landscape of Africa.…”

Section: Effect Of Bantu Expansions On Y Chromosome and Mtdna Variationmentioning

confidence: 99%

Contrasting patterns of Y chromosome and mtDNA variation in Africa: evidence for sex-biased demographic processes

et al. 2005

Self Cite

View full text Add to dashboard Cite

To investigate associations between genetic, linguistic, and geographic variation in Africa, we type 50 Y chromosome SNPs in 1122 individuals from 40 populations representing African geographic and linguistic diversity. We compare these patterns of variation with those that emerge from a similar analysis of published mtDNA HVS1 sequences from 1918 individuals from 39 African populations. For the Y chromosome, Mantel tests reveal a strong partial correlation between genetic and linguistic distances (r ¼ 0.33, P ¼ 0.001) and no correlation between genetic and geographic distances (r ¼ À0.08, P40.10). In contrast, mtDNA variation is weakly correlated with both language (r ¼ 0.16, P ¼ 0.046) and geography (r ¼ 0.17, P ¼ 0.035). AMOVA indicates that the amount of paternal among-group variation is much higher when populations are grouped by linguistics (U CT ¼ 0.21) than by geography (U CT ¼ 0.06). Levels of maternal genetic among-group variation are low for both linguistics and geography (U CT ¼ 0.03 and 0.04, respectively). When Bantu speakers are removed from these analyses, the correlation with linguistic variation disappears for the Y chromosome and strengthens for mtDNA. These data suggest that patterns of differentiation and gene flow in Africa have differed for men and women in the recent evolutionary past. We infer that sex-biased rates of admixture and/or language borrowing between expanding Bantu farmers and local hunter-gatherers played an important role in influencing patterns of genetic variation during the spread of African agriculture in the last 4000 years.

show abstract

“…As mitochondrial genes are inherited from the mother, even complete mixing of males among groups will not affect population structure if females are completely philopatric (Birky et al 1983;Chesser & Baker 1996;Prugnolle & de Meeus 2002). Empirical differences in maternally versus paternally inherited genetic markers have been used to infer the amount of sex-specific migration in humans (Seielstad et al 1998;Wilder et al 2004), chimpanzees (Langergraber et al 2007) and other animals (Baker et al 1998;Natoli et al 2005;Eriksson et al 2006), so similar questions could be addressed using F ST for cultural traits. While innovation may be analogous to mutation, it is unclear how closely the various well-studied models of mutation would correspond to innovation when a trait can have one of many variants or be completely absent.…”

mentioning

confidence: 99%

The effect of innovation and sex-specific migration on neutral cultural differentiation

Yeaman¹,

Bshary²,

Lehmann³

2011

Animal Behaviour

View full text Add to dashboard Cite

Keywords cultural trait population structure sex-biased migration sex-biased social learning Studies of behaviour are increasingly focusing on acquisition of traits through cultural inheritance. Comparison of patterns of spatial population structure (F ST ) between neutral genetic loci and behavioural or cultural traits can been used to test hypotheses about demography, life history, and the mechanisms of inheritance/transmission of these traits in humans, chimpanzees and other animals. Here, we develop analytical expectations to show how F ST in cultural traits can differ strongly from that measured at neutral genetic markers if migration is largely restricted to one sex but social learning is predominantly modelled on the other (e.g. males migrate, females serve as models for cultural traits), if one individual is the learning model for many, or if rates of innovation (individual learning) are high or rates of social learning are low. We discuss how comparisons of F ST between genetic loci and behavioural traits can be applied to evaluate the importance of innovation in shaping patterns of cultural differentiation, as even low rates of innovation can considerably reduce F ST , relative to observed structure at neutral genetic loci. Our results also suggest that differentiation in neutral cultural traits should occur over much smaller scales in species with male migration and female enculturation (or the reverse).

show abstract

Global patterns of human mitochondrial DNA and Y-chromosome structure are not influenced by higher migration rates of females versus males

Cited by 132 publications

References 22 publications

Molecular analysis reveals tighter social regulation of immigration in patrilocal populations than in matrilocal populations

Molecular analysis reveals tighter social regulation of immigration in patrilocal populations than in matrilocal populations

Contrasting patterns of Y chromosome and mtDNA variation in Africa: evidence for sex-biased demographic processes

The effect of innovation and sex-specific migration on neutral cultural differentiation

Contact Info

Product

Resources

About