Global Left Ventricular Longitudinal Systolic Strain for Early Risk Assessment in Patients with Acute Myocardial Infarction Treated with Primary Percutaneous Intervention

Distinct Aspects of Left Ventricular Mechanical Function Are Differentially Associated With Cardiovascular Outcomes and All‐Cause Mortality in the Community

“…This finding is consistent with previous work demonstrating that alterations in longitudinal strain are associated with traditional risk factors for CHD (eg, hypertension) in the absence of overt disease31, 32, 33, 34; in turn, longitudinal strain is also considered among the most sensitive markers of active myocardial ischemia 35, 36. On echocardiography, longitudinal strain is measured along the endocardial surface of the LV cavity, in approximate alignment with the longitudinal orientation of myocardial fibers located along the subendocardial layers of the LV 37.…”

Global left ventricular longitudinal systolic strain as a major predictor of cardiovascular events in patients with atrial fibrillation

“…Compared with tissue Doppler-derived strain, speckle-derived strain does not have angle dependency and is easier to calculate. In addition, several studies have demonstrated that GLS can offer an additional benefit in prediction of CV outcomes over LVEF in various heart diseases such as heart failure,10 11 27 acute myocardial infarction12 and severe aortic stenosis 13. In the present study, we further confirmed that the GLS was an independent prognosticator and stronger than LVEF in predicting CV events in AF.…”

Independent Role of Left Ventricular Global Longitudinal Strain in Predicting Prognosis of Chronic Heart Failure Patients

“…It has been validated by means of sonomicrometry and tagged magnetic resonance imaging 6 and can quantify global and regional cardiac function more accurately and objectively by detecting mild ventricular function abnormalities in both left and right ventricular cardiomyopathies. [9][10][11] It may also play a role in prognostic stratification in various clinical settings, including unselected patients, 22 patients undergoing transcatheter aortic valve replacement, 23 patients with acute myocardial infarction and chronic ischemic heart disease, 24,25 patients who have undergone heart transplantation and heart failure patients. 12,13,26,27 Our findings add new information and represent a further step towards better defining the prognostic significance of strain measures in CHF patients.…”