Abstract. Let X 1 and X 2 be two compact strongly pseudoconvex CR manifolds of dimension 2n − 1 ≥ 5 which bound complex varieties V 1 and V 2 with only isolated normal singularities in C N 1 and C N 2 respectively. Let S 1 and S 2 be the singular sets of V 1 and V 2 respectively and assume S 2 is non-empty. If 2n − N 2 − 1 ≥ 1 and the cardinality of S 1 is less than twice that of S 2 , then we prove that any non-constant CR morphism from X 1 to X 2 is necessarily a CR biholomorphism. On the other hand, let X be a compact strongly pseudoconvex CR manifold of dimension 3 which bounds a complex variety V with only isolated normal non-quotient singularities. Assume that the singular set of V is non-empty. Then we prove that any non-constant CR morphism from X to X is necessarily a CR biholomorphism.