Global initiative for meticillin-resistant Staphylococcus aureus pneumonia (GLIMP): an international, observational cohort study

Aliberti, Stefano; Reyes, Luis Felipe; Faverio, Paola; Sotgiu, Giovanni; Dore, S. E.; Rodríguez, Alejandro; Soni, Nilam J.; Marcos, Pedro J.

doi:10.1016/s1473-3099(16)30267-5

Cited by 114 publications

(93 citation statements)

References 25 publications

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Section: Methodsmentioning

confidence: 99%

“…The present study is a secondary analysis of the database collected for the GLIMP study, an international, multicenter, point-prevalence study of hospitalized adult patients with a diagnosis of CAP [12]. Detailed methodology of the GLIMP study was published elsewhere [12]. The study was conducted in accordance with the amended Declaration of Helsinki and was approved by the Institutional Review Board (IRB# HSC20150184E) of The University of Texas Health Science Center at San Antonio, TX, USA, and all participating centers were required to comply with local, regional, or national research regulations to participate in the study.…”

Section: Methodsmentioning

confidence: 99%

“…All antimicrobial, antiviral, and antifungal treatments administered within 24 h from the admission were recorded. Data were collected and managed using an ad hoc report form and a dedicated data capture tool [12].…”

Section: Data Collectionmentioning

confidence: 99%

See 2 more Smart Citations

An international perspective on hospitalized patients with viral community-acquired pneumonia

Radovanovic¹,

Sotgiu²,

Janković³

et al. 2019

European Journal of Internal Medicine

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

An international perspective on hospitalized patients with viral community-acquired pneumonia

Radovanovic¹,

Sotgiu²,

Janković³

et al. 2019

European Journal of Internal Medicine

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“…Recently, Aliberti et al . globally investigated the prevalence of MRSA pneumonia in hospitalized patients with community‐onset pneumonia . They reported that the prevalence of MRSA infection in the culture‐positive cohort was 8.1% and the percentages differed among regions: 6.1%, 6.8%, 7.4%, 7.7%, 15.3% and 16.4% in Europe, Africa, Asia, Oceania, South America and North America, respectively (Fig.…”

Section: Regional Differences In the Prevalence Of Drps In Community‐mentioning

confidence: 99%

“…They reported that the prevalence of MRSA infection in the culture‐positive cohort was 8.1% and the percentages differed among regions: 6.1%, 6.8%, 7.4%, 7.7%, 15.3% and 16.4% in Europe, Africa, Asia, Oceania, South America and North America, respectively (Fig. ) …”

Section: Regional Differences In the Prevalence Of Drps In Community‐mentioning

confidence: 99%

Regional differences in antibiotic‐resistant pathogens in patients with pneumonia: Implications for clinicians

Shindo

Hasegawa

2017

Respirology

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Antibiotic resistance is of great concern for both infection control and the treatment of infectious diseases. Previous studies reported that the occurrence of drugresistant pathogens (DRPs)-for instance, methicillinresistant Staphylococcus aureus (MRSA), Pseudomonas aeruginosa and extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae-were associated with inappropriate antibiotic treatment that resulted in adverse outcomes. In addition, unnecessary use of broad-spectrum antibiotics for patients with non-DRPs increased mortality. Therefore, the assessment of risk for DRPs at diagnosis is critical to avoid patients' adverse events. In the present review, we discuss regional differences in the prevalence of DRPs, which ranged from 6% to 45%, in patients with communityonset pneumonia, including both community-acquired and healthcare-associated pneumonia. We then introduce the reported risk factors for DRPs in those patients, and present proposed prediction models for identifying patients with DRPs at diagnosis. Physicians should be aware that some of the risk factors for DRPs (e.g. prior antibiotic use and prior hospitalization) were common between regions; however, others may be different or the weighting of the risks may vary, even for the same risk factors. Therefore, a specific evaluation of risk factors for DRPs is recommended for each region and institution. Furthermore, we present a possible strategy for initial antibiotic selection in patients with community-onset pneumonia, considering DRPs risk. We also discuss future directions for the study of DRPs in community-onset, hospital-acquired and ventilatorassociated pneumonia to improve the management of patients with pneumonia.

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Rapid identification of methicillin‐resistant Staphylococcus aureus by MALDI‐TOF MS: A meta‐analysis

Chen

Zhou

Liu

et al. 2023

Biotech and App Biochem

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Invasive infections caused by methicillin‐resistant Staphylococcus aureus (MRSA) are associated with high mortality and morbidity. The sooner the pathogen is determined, the better it is beneficial to patient. However, routine laboratory inspections are time‐consuming and laborious. A thorough research was conducted in PubMed and Web of Science (until June 2021) to identify studies evaluating the accuracy of MRSA identification by matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry (MALDI‐TOF MS). STATA 15.0 software was used to analyze the pooled results of sensitivity, specificity, and 95% confidence intervals (CI). The summary receiver operating characteristic curves (SROC) and area under the curve (AUC) were utilized to show the overall performance of MALDI‐TOF MS. Fifteen studies involving 2471 isolates were included in this study after the final selection in this meta‐analysis. Using the random effects model forest plot to summarize the overall statistics, the sensitivity of MALDI‐TOF MS for identifying MRSA was 92% (95% CI: 81%–97%), and the specificity was 97% (95% CI: 89%–99%). In the SROC curve, the AUC reached 0.99 (95% CI: 97%–99%). Deeks’ test showed no significant publication bias in this meta‐analysis. Compared with clinical reference methods, MALDI‐TOF MS identification of MRSA shows a higher degree of sensitivity and specificity.

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Global initiative for meticillin-resistant Staphylococcus aureus pneumonia (GLIMP): an international, observational cohort study

Cited by 114 publications

References 25 publications

An international perspective on hospitalized patients with viral community-acquired pneumonia

An international perspective on hospitalized patients with viral community-acquired pneumonia

Regional differences in antibiotic‐resistant pathogens in patients with pneumonia: Implications for clinicians

Rapid identification of methicillin‐resistant Staphylococcus aureus by MALDI‐TOF MS: A meta‐analysis

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