Global disparities in the epilepsy treatment gap: a systematic review

Meyer, Ana-Claire; Dua, Tarun; Ma, Juliana; Saxena, Shekhar; Birbeck, Gretchen L.

doi:10.2471/blt.09.064147

Cited by 363 publications

(351 citation statements)

References 44 publications

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“…About three fourths of people with epilepsy living in low-and middle-income countries do not get the treatment they need because antiepileptic drugs are inaccessible or too expensive. 1, 3,4 Nevertheless, not all patients respond to available medical treatments, with increasing evidence that surgery and other treatments (e.g. neurostimulation and diet) can be beneficial.…”

Section: Introductionmentioning

confidence: 99%

Knowledge and attitude towards epilepsy among pharmacy students from Mumbai university

Limaye¹,

Deshpande²,

Gite³

et al. 2018

Int J Res Med Sci

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Background: Epilepsy is a chronic disorder of the brain that affects people worldwide. The overall prevalence (3.0-11.9 / 1,000) and incidence (0.2-0.6/1,000) of epilepsy in India are comparable to the rates of high-income countries. The high prevalence of negative attitudes towards epilepsy has been highlighted by several studies. Pharmacy students represent a better-educated section of society regarding drugs and have the potential to create awareness, and influence attitudes towards the disease. Thus, it is important that they have the appropriate and updated knowledge and appropriate attitude towards epilepsy and antiepileptic drugs. Objective of the present study was to determine the Mumbai University pharmacy student’s awareness about epilepsy, so as to know the kind of education and awareness strategies that would be applicable to them.Methods: A cross-sectional study was carried out among students from Mumbai University, India during May-June 2017. Two hundred and fifty students were approached to participate in the study of which 213 agreed to participate (males: 107; females: 106). Pretested questionnaire was distributed and collected data was analyzed using IBM SPSS version 23.Results: Response rate for this study was 85.2% (213/250). Ninety six percent (204/213) of the participants had heard or read about epilepsy. Overall knowledge was poor (40.2%) and attitude was fair (75.3%). None of the participants were aware about recent research regarding hereditary nature of epilepsy. Only 2 (0.98%) students were aware how to perform the first aid in epilepsy. Only 6.8% participants felt that epileptics should participate in sports.Conclusions: The findings of this study show that, even with extensive curriculum covering diseases, drugs and relevant laws of land, the knowledge and attitude scores were low. There is a need to have focused education and campaigns to increase the knowledge and attitude towards epilepsy.

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Section: Introductionmentioning

confidence: 99%

Knowledge and attitude towards epilepsy among pharmacy students from Mumbai university

Limaye¹,

Deshpande²,

Gite³

et al. 2018

Int J Res Med Sci

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“…This 90% treatment gap was corroborated by studies from northern and southern Tanzania showing that 76% and 95% of people with epilepsy, respectively, had not been treated [12,19]. Dramatic global disparities in this treatment gap were identified by a systematic review which showed that 75% and fewer than 10% of PWE from low-income and high-income countries, respectively, were untreated or insufficiently treated for their epilepsy [36]. A recent study from Kenya demonstrated an epilepsy treatment gap of 62% using serum antiepileptic drug levels as a measure of compliance and found that self-reporting of compliance to antiepileptic medication was very unreliable when compared to the serum antiepileptic drug levels [37,38].…”

Section: Treatment Gap Of Epilepsy In Sub-saharan Africamentioning

confidence: 66%

Epilepsy and neurocysticercosis in sub-Saharan Africa

Winkler

Willingham

Sikasunge

et al. 2009

Wien Klin Wochenschr

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“…In stark contrast, many high‐income countries have a treatment gap of less than 10% 1. This disparity is especially unfortunate in view of the fact that epilepsy treatment is inexpensive.…”

Section: Health and Economic Burden Of Epilepsymentioning

confidence: 99%

Defeating epilepsy: A global public health commitment

Saxena

2017

Epilepsia Open

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SummaryThis article points out that defeating epilepsy is a global public health commitment and a new challenge. This is because: epilepsy causes a heavy burden and very high treatment gap; in the field of life sciences and medicine, the 21st century would be the “Century of Brain Science”; a number of national brain research initiatives provide a great opportunity to reveal the secret of epilepsy; the Global Campaign against Epilepsy and the Mental Health Gap Action Programme made great contributions in the epilepsy control work worldwide; the historical WHA68.20 resolution gives great strength to promote defeating epilepsy.

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Global disparities in the epilepsy treatment gap: a systematic review

Cited by 363 publications

References 44 publications

Knowledge and attitude towards epilepsy among pharmacy students from Mumbai university

Knowledge and attitude towards epilepsy among pharmacy students from Mumbai university

Epilepsy and neurocysticercosis in sub-Saharan Africa

Defeating epilepsy: A global public health commitment

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