Global Demographic Characteristics and Pathogen Spectrum of Tinea Capitis

Chen, Xiaoqing; Yu, Jin

doi:10.1007/s11046-023-00710-8

Cited by 2 publications

(1 citation statement)

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“…Consistent with previous findings, 17,19,20 adult kerion patients were relatively rare, probably due to the protective effects of fungistatic free fatty acids in the sebum and colonisation by Pityrosporum orbicularae 21,22 . The higher incidence of anthropophilic infection in adults was possibly linked to a higher proportion of concurrent dermatophytosis 23–25 .…”

Section: Discussionsupporting

confidence: 89%

Epidemiologic features and therapeutic strategies of kerion: A nationwide multicentre study

Deng,

Chen,

Zheng

et al. 2024

Mycoses

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BackgroundKerion is a severe type of tinea capitis that is difficult to treat and remains a public health problem.ObjectivesTo evaluate the epidemiologic features and efficacy of different treatment schemes from real‐world experience.MethodsFrom 2019 to 2021, 316 patients diagnosed with kerion at 32 tertiary Chinese hospitals were enrolled. We analysed the data of each patient, including clinical characteristics, causative pathogens, treatments and outcomes.ResultsPreschool children were predominantly affected and were more likely to have zoophilic infection. The most common pathogen in China was Microsporum canis. Atopic dermatitis (AD), animal contact, endothrix infection and geophilic pathogens were linked with kerion occurrence. In terms of treatment, itraconazole was the most applied antifungal agent and reduced the time to mycological cure. A total of 22.5% of patients received systemic glucocorticoids simultaneously, which reduced the time to complete symptom relief. Furthermore, glucocorticoids combined with itraconazole had better treatment efficacy, with a higher rate and shorter time to achieving mycological cure.ConclusionsKerion often affects preschoolers and leads to serious sequelae, with AD, animal contact, and endothrix infection as potential risk factors. Glucocorticoids, especially those combined with itraconazole, had better treatment efficacy.

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Section: Discussionsupporting

confidence: 89%