Global Declines in Vaccine Confidence from 2015 to 2022: A Large-Scale Retrospective Analysis

Wiegand, M.; Eagan, R.; Karimov, R. Kh.; Lin, Leesa; Larson, Heidi J.; Figueiredo, Alexandre de

doi:10.2139/ssrn.4438003

Cited by 12 publications

(8 citation statements)

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“…In addition, clear evidence-based recommendations and consistent messaging on vaccines are essential to increase vaccine confidence among HCPs and patients. 34–36…”

Section: Discussionmentioning

confidence: 99%

“…In addition, clear evidence-based recommendations and consistent messaging on vaccines are essential to increase vaccine confidence among HCPs and patients. [34][35][36] The clinical understanding of the viral mutations, at-risk population, long-term complications, and optimal vaccine schedule for COVID- The 6-month study period used in this analysis did not capture the full 2022-2023 influenza season as defined by the CDC. However, the peak influenza period is captured in this analysis, and the exclusion of the tail end of the season should not be expected to significantly change the results.…”

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confidence: 99%

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Comparison of COVID-19 and Influenza-Related Outcomes in the United States during Fall-Winter 2022-2023

Kopel,

Bogdanov,

Winer-Jones

et al. 2023

Preprint

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BackgroundThree years into the pandemic, SARS-COV-2 remains a significant burden in comparison to other respiratory illnesses; however, many of the monitoring tools available during the early phase of the COVID-19 pandemic have been phased out, making it more difficult to track the current burden of outpatient medical encounters and hospitalizations, especially for at-risk groups. The objective of this analysis was to characterize the frequency and severity of medically-attended COVID-19 and influenza during peak influenza activity in the pediatric (0-17), adult (18-64), and older adult (65+) populations and characterize the prevalence of underlying medical conditions among patients hospitalized with COVID-19.MethodsThis was a cross-sectional analysis of individuals in the Veradigm Health Insights EHR Database linked to Komodo claims data with a medical encounter of claim between October 1, 2022, and March 31, 2023. We captured age, sex, and underlying medical conditions associated with higher risk for severe COVID-19 during a 12-month baseline period. We identified patients with medical encounters with a diagnosis of COVID-19 or influenza between October 1, 2022, and March 31, 2023, and stratified them into 5 mutually exclusive categories based on the highest level of care received with that diagnosis during the season (intensive care unit [ICU] > hospitalization without ICU > emergency department > urgent care > other outpatient).ResultsAmong the 23,526,196 individuals in the dataset, 5.0% had a COVID-19-related medical encounter, and 3.0% had an influenza-related medical encounter during the 6 month observation period. The incidence of hospitalizations with a COVID-19 diagnosis was 4.6 times higher than the incidence of hospitalizations with an influenza diagnosis. Hospitalizations with COVID-19 were higher in all age groups. Nearly all adults hospitalized with COVID-19 had at least one underlying medical condition, but 25.8% of 0-5-year-olds and 18.3% of 6-17-year-olds had no underlying medical conditions.ConclusionsCOVID-19 continues to place a heavy burden on the United States healthcare system and was associated with more medical encounters in all age groups, including hospitalizations, than influenza during a 6-month period that included the 2022-2023 peak influenza activity.

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“…In addition, clear evidence-based recommendations and consistent messaging on vaccines are essential to increase vaccine confidence among HCPs and patients. 34–36…”

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Comparison of COVID-19 and Influenza-Related Outcomes in the United States during Fall-Winter 2022-2023

Kopel,

Bogdanov,

Winer-Jones

et al. 2023

Preprint

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“…These factors affect each other in complex and interactive ways, shaping an individual's vaccination readiness. Previous studies reported that Japan has one of the lowest confidence levels in general vaccines worldwide (1,14). However, the status of the other factors and the pattern of the seven factors comprising general vaccination readiness remain unclear.…”

Section: A N U S C R I P Tmentioning

confidence: 99%

General Vaccination Readiness in Japan: Results from the JASTIS 2023 Study

Machida,

Inoue,

Tabuchi

2024

Jpn J Infect Dis

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General vaccine hesitancy is a global concern. Clarification of the general vaccination readiness and psychological factors comprising it is an important issue. Previous studies have reported that Japan has one of the lowest vaccine confidence levels worldwide. However, the status of other psychological factors comprising general vaccination readiness in Japan remains unclear.Therefore, we aimed to clarify the status of seven psychological factors comprising general vaccination readiness and their patterns in Japan. This descriptive study utilized data from a largescale nationwide internet survey (JASTIS 2023 study, n = 31,037). The seven psychological factors were assessed using the 7C of vaccination readiness scale. Cluster analysis was performed using k-means++ clustering to clarify the patterns. Of the seven factors, support for social monitoring of people refusing vaccination (e.g., vaccine passport) was very low among the participants. Cluster analysis showed that the participants' vaccination readiness could be classified into six patterns, of which the very low vaccination readiness cluster, with the lowest scores for most of the psychological factors, accounted for 11.1% and was more common among those aged 30-49 years (13.1-16.4%). Individuals comprising this cluster may tend to refuse to receive any recommended vaccines.

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“…There was a measurable drop in confidence in 46 of 55 countries. 11 , 12 Addressing these existing immunity and coverage gaps will require a change in vaccination strategies, an increase in further immunisation catch-ups through campaigns or intensified routine-immunisation activities, and strong political commitment to the WHO Immunization Agenda 2030. Future efforts by global partners to restore coverage losses were announced in April, 2023.…”

Section: Introductionmentioning

confidence: 99%

Estimating the health effects of COVID-19-related immunisation disruptions in 112 countries during 2020–30: a modelling study

Hartner,

Li,

Echeverria-Londono

et al. 2024

The Lancet Global Health

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Global Declines in Vaccine Confidence from 2015 to 2022: A Large-Scale Retrospective Analysis

Cited by 12 publications

References 0 publications

Comparison of COVID-19 and Influenza-Related Outcomes in the United States during Fall-Winter 2022-2023

Comparison of COVID-19 and Influenza-Related Outcomes in the United States during Fall-Winter 2022-2023

General Vaccination Readiness in Japan: Results from the JASTIS 2023 Study

Estimating the health effects of COVID-19-related immunisation disruptions in 112 countries during 2020–30: a modelling study

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