Global Cancer Consortiums: Moving from Consensus to Practice

Ilbawi, André; Anderson, Benjamin O.

doi:10.1245/s10434-014-4346-6

Cited by 10 publications

(18 citation statements)

References 60 publications

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“…GCCs provide structure that organize existing information, capitalize on synergies, and work toward consensus of overarching core concepts while also allowing each organization to adapt based on their own needs and resources (Ilbawi & Anderson, ). The GCCs also provide the framework for effective implementation in the form of generalizable data; accepted standards of care; education; technology transfer; monitoring of outcomes; and engagement of diverse and equitable stakeholders including healthcare providers, community members, and governmental officials (Al‐Adsani et al, ; Ilbawi & Anderson, ; Trimble et al, ). Some key lessions for PND research are the importance of developing consensus guidelines, providing overarching frameworks that define best practices for each step of translational research from bench to biobanking to working with community organizations and government.…”

Section: Building On Current Foundationsmentioning

confidence: 99%

Toward a framework for best practices and research guidelines for perinatal depression research

Kimmel

Bauer

Meltzer‐Brody

2019

J of Neuroscience Research

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This review article highlights the current state of perinatal depression (PND) research including established standards of care and innovative research in progress. PND can have a significant adverse impact on mother, child, and family; however, to date, wide‐scale identification, prevention, and treatment have been limited. PND is heterogenous in presentation with likely multifactorial etiologies for each woman. Challenges in PND research are discussed including a need for universal tools, standardized measures, benchmarks, and best practices. Current examples are reviewed that highlight approaches to novel treatment paradigms and interventions. This includes reviewing epidemiologic studies in PND research, examining the biological underpinnings of PND, and discussing examples from this field and other fields currently developing translational research that spans from bench to bedside. Current and future challenges and opportunities in developing best practices for the treatment of PND are outlined. We also discuss the use of the NIMH Research Domain Criteria approach for PND research and provide recommendations for future directions in PND research collaboration. In conclusion, greater precision in perinatal psychiatry can be possible in the future with the development of guidelines and best practices that build on current work and apply innovative and collaborative approaches of scientists, providers, patients, community members, and government officials.

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Section: Building On Current Foundationsmentioning

confidence: 99%

Toward a framework for best practices and research guidelines for perinatal depression research

Kimmel

Bauer

Meltzer‐Brody

2019

J of Neuroscience Research

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“…(104) This demands a collaborative effort that draws on the collective expertise and resources of individuals and institutions engaged in breast cancer care. (105) Future directions will hinge on identifying individualized approaches based upon building functional systems that provide effective early detection, diagnosis and treatment approaches based upon the implementation of existing resources. (106)…”

Section: Disparities Around the Globementioning

confidence: 99%

Breast Cancer Disparities at Home and Abroad: A Review of the Challenges and Opportunities for System-Level Change

Reeder‐Hayes

Anderson

2017

Clinical Cancer Research

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Sizeable disparities exist in breast cancer outcomes, both between Black and White patients in the United States, and between patients in the US and other high-income countries compared to low- and middle-income countries (LMICs). In both settings, health system factors are key drivers of disparities. In the US, Black women are more likely to die of breast cancer than Whites, and have poorer outcomes even among patients with similar stage and tumor subtype. Over-representation of higher-risk “triple negative” breast cancers contributes to breast cancer mortality in Black women; however, the greatest survival disparities occur within the good-prognosis hormone-receptor positive (HR+) subtypes. Disparities in access to treatment within the complex US health system may be responsible for a substantial portion of these differences in survival. In LMICs, breast cancer mortality rates are substantially higher than in the US, while incidence continues to rise. This mortality burden is largely attributable to health system factors, including late-stage presentation at diagnosis and lack of availability of systemic therapy. This article will review the existing evidence for how health-system factors in the United States contribute to breast cancer disparities, discuss methods for studying the relationship of health system factors to racial disparities, and provide examples of health system interventions that show promise for mitigating breast cancer disparities. We will then review evidence of global breast cancer disparities in low and middle income countries, the treatment factors that contribute to these disparities, and actions being taken to combat breast cancer disparities around the world.

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“…1 The authors provide a detailed and clear description of the opportunities and challenges associated with global efforts aimed at reducing cancer inequities in low-and middle-income countries (LMICs). They highlight the importance of joining forces, as in today's complex world individual efforts can produce only limited accomplishments.…”

Section: To the Editorsmentioning

confidence: 99%