Global aphasia in a case of bilateral frontal lobe infarcts involving both caudate nuclei

Karthik, Davala Krishna; Khardenavis, Vikram; Kulkarni, Sharvari; Deshpande, Anirudda

doi:10.1136/bcr-2017-221642

Cited by 2 publications

(1 citation statement)

References 2 publications

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“…Global aphasia is caused by large lesions that can be found in numerous locations. The lesion locations include the frontal lobe, parietal lobe, occipital lobe, insula, internal capsule, basal ganglia, thalamus, caudate and lentiform nuclei, corpus callosum, centrum semiovale, and corona radiata (Bohra et al 2015, Kang et al 2017, Krishna Karthik et al 2017).…”

Section: Lesion Locations In Patients With Global Aphasiamentioning

confidence: 99%

Characteristics of Aphasia in Ischemic Stroke Patients at Dr. Mahar Mardjono National Brain Center Hospital Indonesia in 2021

Rasya Hapsari Danardhono,

Arman Yurisaldi Saleh,

Ria Maria Theresa

et al. 2023

FMI

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Highlights: 1. To author’s knowledge, this study is the first study done in National Brain Center Hospital In Jakarta2. No similar studies have been done during the pandemic era3. This study can add additional data to further studies about aphasia in comparison with post pandemic era Abstract Global aphasia, sensory transcortical aphasia, motor transcortical aphasia, motor aphasia, sensory aphasia, conduction aphasia and anomic aphasia can occur in ischemic stroke. There are different locations of lesions in each type of aphasia. There has been an increase in incidence and mortality of stroke patients during the COVID-19 pandemic. Before the pandemic, global aphasia was the most common type of aphasia. This study was conducted to determine the type of aphasia, clinical and radiological features, and also management of aphasia in ischemic stroke during the pandemic. This research is a descriptive study with a cross sectional approach. Sampling was done by total sampling technique. The research sample was ischemic stroke subjects with aphasia diagnosed from January 1, 2021 - December 31, 2021 at the National Brain Center Hospital Prof. Dr. dr. Mahar Mardjono Jakarta. Statistical analysis was done using IBM SPSS Statistics for Mac, Version 25.0 (IBM Corp., Armonk, N.Y., USA). There were 162 aphasic subjects with ischemic stroke. Age range was 34 – 87 years. Most subjects were male (59.9%), aged 55-65 years (37.0%). Hypertension (90.1%), diabetes mellitus (50.0%), and dyslipidemia (75.9%) were the dominant risk factors. The most common type of aphasia is global aphasia (43.8%) and motoric aphasia. (33,3%). The parietal lobe was the dominant location of global aphasia (38 subjects) and motoric aphasia (47 subjects). The therapy given to aphasic subjects with a history of ischemic stroke includes speech therapy (85.2%), antiplatelet therapy (98.1%), anticoagulants (19.1%), rTPA (1.2%), and neuroprotectors (3.0 %). In conclusion, in ischemic stroke subjects with aphasia at the National Brain Center Hospital during the pandemic, global aphasia was found to be the most common with the dominant global aphasia lesion location in the parietal lobe.

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Section: Lesion Locations In Patients With Global Aphasiamentioning

confidence: 99%

Characteristics of Aphasia in Ischemic Stroke Patients at Dr. Mahar Mardjono National Brain Center Hospital Indonesia in 2021

Rasya Hapsari Danardhono,

Arman Yurisaldi Saleh,

Ria Maria Theresa

et al. 2023

FMI

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Kaudat Nukleus Bağlanti Yollari Mi̇krocerrahi̇ Anatomi̇si̇’ni̇n Psi̇koşi̇rürji̇kal Önemi̇: Özgün Kadavra Araştirma Çalişmasi

Biçeroğlu

2020

SDÜ Tıp Fakültesi Dergisi

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AmaçNükleus kaudatus bazı nörolojik ve psikiyatrik hastalıkların tedavisinde bir hedef olabilir mi diye tartışılmaktadır. Mikrocerrahi girişimler ve stereotaksik yaklaşımlar için kaudat nükleus bağlantılarının daha açık bir şekilde tanımlanması gerekmektedir. Bu çalışmamızda nükleus kaudatus mikrocerrahi anatomisini ve bağlantı yollarını fiber diseksiyon tekniği kullanarak ortaya koymayı ve bunun psikoşirürjikal önemini orrtaya koymayı amaçladık. Gereç ve YöntemDört adet formalinle fikse edilmiş insan beyni (8 hemisfer) detaylı şekilde incelendi. Tüm örnekler Klingler' in tekniğine göre -16 °C'de en az 15 gün donduruldu ve birkaç saat boyunca su altında çözülmeleri sağlandı. X6 ila x40 mikroskopik büyütme altında ak madde lif diseksiyonu gerçekleştirildi. Tüm beyin hemisferleri, lateralden mediale doğru kaudat nükleusun başı ve gövdesi ortaya çıkana kadar olarak disseke edildi. Ayrıca, adım adım iki ve üç boyutlu fotoğraflar çekildi. BulgularNükleus kaudatus etrafındaki tüm yapılar kademeli olarak diseke edildi. Bu yapı ile iletişim halinde olan ve fiziksel olarak temas eden tüm kortikal alanlar göz-den geçirildi. Frontokaudat ve frontotemporal bağlantıların mikrocerrahi anatomisi ayrıntılı ortaya konuldu. SonuçPsikoşirürji, medikal tedavilerin henüz gelişmediği dönemlerde, depresyon tedavisinde öncelikli olarak kullanılmıştır. Kaudat nükleusa yönelik yapılan derin beyin stimülasyonu klinik pratikte standart bir tedavi yöntemi değildir ama Parkinson hastalığı, obsesif kompülsif hastalık ve majör depresyonda alternatif tedavi olabilir.

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Global aphasia in a case of bilateral frontal lobe infarcts involving both caudate nuclei

Cited by 2 publications

References 2 publications

Characteristics of Aphasia in Ischemic Stroke Patients at Dr. Mahar Mardjono National Brain Center Hospital Indonesia in 2021

Characteristics of Aphasia in Ischemic Stroke Patients at Dr. Mahar Mardjono National Brain Center Hospital Indonesia in 2021

Kaudat Nukleus Bağlanti Yollari Mi̇krocerrahi̇ Anatomi̇si̇’ni̇n Psi̇koşi̇rürji̇kal Önemi̇: Özgün Kadavra Araştirma Çalişmasi

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