Glistening formation in a new hydrophobic acrylic intraocular lens

Abstract

Background: The formation of fluid-filled microvacuoles, termed glistenings, is a common complication of intraocular lenses (IOLs) made from hydrophobic acrylate. Using our well-established in-vitro laboratory method, we evaluated a new IOL material’s resistance to glistening formation.Methods: An in-vitro stress test for glistening induction was performed on twenty samples of hydrophobic acrylic IOLs: ten of the new Eyecryl ASHFY600 (Biotech Vision Care, Ahmedabad, India) compared with ten samples of AcrySof IQ SN60WF (Alcon, Fort Worth, USA). The number of microvacuoles per square millimetre (MV/mm2) was evaluated in five sections of each IOL. The results for each model were compared and rated on the Miyata Scale for grading glistening severity.Results: In all cases, glistening number was higher in the central section of the IOL optic than in the periphery. Mean number of MV/mm2 was highest in the central part of the AcrySof IQ SN60WF, with 41.84 (±27.67) MVs/mm². The lowest number of glistenings was found in the five sections of the Eyecryl ASHFY600 with 0.52 (±0.24) MVs/mm². Mean value of the Eyecryl ASHFY600 IOL, using the Miyata Scale, was Zero.Conclusion: In this in-vitro laboratory study, the new hydrophobic acrylic IOL showed a high resistance to microvacuole formation. Results from this in-vitro study suggest that glistening numbers will be low in clinical use in the Eyecryl ASHFY600.

Comparison of 3-month visual outcomes of a new multifocal intraocular lens vs a trifocal intraocular lens

“…7 In addition, a 3-month follow-up limits the assessment of long-term effects observed with AcrySof material, such as that of lens glistenings that have been shown to increase light scatter and may potentially reduce vision quality over time. 8,9 Moreover, recent studies suggest that IOL glistening will continue to increase over time rather than plateau. 10,11 Previously published studies of the ZFR00V IOL and other presbyopia-correcting IOLs support the CDVA findings of this study.…”

Etiology, pathogenesis, and management of acute intraocular lens opacification: a systematic review

“…Corticosteroids have a leading role in the management. Regardless to the shape, productive company, material properties, and surface technology of materials, acute IOL discoloration can be occurred in almost all types of IOLs such as hydrophilic acrylic IOL, acrylic hydrophobic IOL, hydrophilic acrylic IOL with a hydrophobic surface, trifocal IOL, silicone IOL, and PMMA IOL [14][15][16][17][18][20][21][22][23][24][53][54][55][56][57] . However, some types of discoloration are more common is some particular types of IOLs.…”