Glioma actively orchestrate a self-advantageous extracellular matrix to promote recurrence and progression
Ruolun Wei,
Jiasheng Zhou,
Brandon Bui
et al.
Abstract:The intricate interplay between cancer cells and their surrounding microenvironment has emerged as a critical factor driving the aggressive progression of various malignancies, including gliomas. Among the various components of this dynamic microenvironment, the extracellular matrix (ECM) holds particular significance. Gliomas, intrinsic brain tumors that originate from neuroglial progenitor cells, have the remarkable ability to actively reform the ECM, reshaping the structural and biochemical landscape to the… Show more
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