“…In this regard, it is considered that younger patients presenting with acute signs and symptoms of neurologic disease are investigated earlier, and consequently, referred more promptly for treatment (9). Conversely, patients with organic brain lesions in neurologically silent brain areas might present with milder 7 symptoms and/or isolated psychiatric symptoms such as depression, anxiety disorders, schizophrenia, anorexia nervosa, or cognitive dysfunction (10,11). In such later cases, differential diagnosis between a brain tumor vs. a psychiatric disorder is required, final diagnosis being frequently delayed for variable periods of time (2,12).…”