Glioblastoma Associated With Intratumoral Abscess Formation

Development of Glioblastoma after Treatment of Brain Abscess

“…17 In the reported cases of abscess formation within glioblastoma, glial scar was not detected, although inflammation findings, such as the infiltration of neutrocytes, were detected. 2,3,6 In our case, the histologic proof of glial scarring within the tumor supports the notion of de novo glioblastoma after brain abscess.…”

“…[1][2][3][4][5][6] In all cases except 1, previous systemic infection was observed. Of the 6 cases, 2 underwent DWI, which, unlike our case, showed lesions with slightly heterogeneous hyperintensity.…”

“…[1][2][3][4][5][6]21,22 Among these cases, intrasellar or parasellar tumors are the most common neoplasms as direct extensions from infected paranasal sinuses. Other neoplasms with abscess formation, such as gliomas, meningiomas, and metastatic brain tumors, also have been rarely reported.…”

“…Glioblastoma with abscess formation is extremely rare and only a few cases have been reported. [1][2][3][4][5][6] The preoperative diagnosis of abscess formation within a glioblastoma is difficult. The diagnosis is usually made during tumor extirpation, without preoperative recognition of the abscess.…”

“…The diagnosis is usually made during tumor extirpation, without preoperative recognition of the abscess. 2,3,6 In a few reported cases, the initial diagnosis was solely brain abscess and patients underwent aspiration of the cyst. 1,5 In these cases, the lesion recurred after a short period, necessitating extirpation of the lesion when the diagnosis of glioblastoma was made.…”