Glial heterotopia of maxilla: A clinical surprise

Mahalik, Santosh Kumar; Lyngdoh, Toijam Soni; Menon, Prema; Sodhi, Kushaljit Singh; Vashishta, Rakesh Kumar; Kanojia, Ravi Prakash; Rao, K. L. N.

doi:10.4103/0971-9261.78132

Cited by 7 publications

(5 citation statements)

References 6 publications

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“…NGH grows slowly and benignly, with no possibility of malignant transformation. [ 18 ] However, early surgical treatment is advocated because the growth of gliosis may lead to deformity and erosion of the facial bones. [ 18 ] Furthermore, early surgical treatment may avoid serious complications such as meningitis, brain abscess, nasal septum and nasal bone deformation.…”

Section: Discussionmentioning

confidence: 99%

“…[ 18 ] However, early surgical treatment is advocated because the growth of gliosis may lead to deformity and erosion of the facial bones. [ 18 ] Furthermore, early surgical treatment may avoid serious complications such as meningitis, brain abscess, nasal septum and nasal bone deformation. [ 19 ] The specific surgical method should be determined in accordance with the location and size of the mass.…”

Section: Discussionmentioning

confidence: 99%

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Intranasal glial heterotopia in a male infant

Zhang

Tang²,

Wang³

et al. 2020

Medicine

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Rationale: Nasal glial heterotopia is a rare type of neoplasm consisting of meningothelial and/or neuroglial elements. Patient concerns: A 2-month-old male was evaluated for treatment of a congenital mass in the right nasal cavity near the pharynx. Diagnoses: The patient was preoperatively diagnosed with a congenital intranasal neoplasm. Interventions: Nasal endoscopic resection of the nasopharyngeal mass was performed under general anesthesia. Histological examination of the resected tissue provided a diagnosis of intranasal glial heterotopia. Outcomes: The surgical outcome was good, with no surgical site infection. After 1 year of follow-up, the boy was asymptomatic with no recurrence. Lessons: Excision of a nasopharyngeal mass via nasal endoscopy resulted in no recurrence during 1 year of follow-up. Before any surgical treatment for suspected glial heterotopia, the mass should be differentiated clinically and radiologically from an encephalocele to prevent the risk of cerebrospinal fluid leakage and meningitis.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Intranasal glial heterotopia in a male infant

Zhang

Tang²,

Wang³

et al. 2020

Medicine

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“…Extranasal sites of glial heterotopia include lung, uterine cervix, endometrium, lip, tongue, and maxilla. [ 8 ]…”

Section: Discussionmentioning

confidence: 99%

A rare case of nasal glial heterotopia in an infant

Tahlan

Tanveer

Kumar

et al. 2020

J Cutan Aesthet Surg

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Glial heterotopias are the displacement of neuroglial tissue in extracranial sites. Nasal glial heterotopias can be of three types-extranasal, intranasal and mixed. Root of the nose is the most common location. These are rare anomalies with an incidence of 1 case in 20,000–40,000 live births. Here we report the case of a 6-month-old infant with a congenital mass located at the root of the nose. Non-contrast computed tomography studies showed no evidence of intracranial communication of the lesion. The mass was excised, and on histopathological examination, it showed glial tissue with astrocytes in a fibrillary background and fibroconnective tissue. Masson’s trichrome stain showed the red staining of the glial tissue, whereas the background fibrosis was stained blue. On immunohistochemistry, glial fibrillary acidic protein was positive. Hence, the diagnosis of nasal glial heterotropia was made. The patient had an uneventful postoperative period.

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“…Glial heterotopia needs to be differentiated from encephalocele to which it is pathologically related because of the risk of cerebrospinal fluid leak and meningitis associated with the later. [ 8 ]…”

Section: Discussionmentioning

confidence: 99%

“…Early surgical intervention is advocated as there is a chance of distortion and erosion of the facial bone due to the growth of glial heterotopias. [ 8 ] Preoperative evaluation by CT and magnetic resonance imaging helps in determining the exact extent and location of the mass and to rule out any contiguity with the central nervous system. Biopsy or fine-needle aspiration is contraindicated unless an intracranial connection is ruled out by imaging studies.…”

Section: Discussionmentioning

confidence: 99%

Bilateral orbital glial heterotopia: A rare case report

Okonkwo

Afghani²,

Akbar³

et al. 2018

Oman J Ophthalmol

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Glial heterotopia is a rare congenital mass that often presents as a unilateral mass lesion in or around the nose. Complete surgical excision is the treatment of choice. However, before any surgical intervention for suspected glial heterotopia, distinction should be made both clinically and radiologically from the pathologically related encephalocele to prevent the risk of cerebrospinal fluid leak and meningitis. Here, we report a rare case of bilateral orbital glial heterotopia in a 2-year-old child with review of the literature.

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Glial heterotopia of maxilla: A clinical surprise

Cited by 7 publications

References 6 publications

Intranasal glial heterotopia in a male infant

Intranasal glial heterotopia in a male infant

A rare case of nasal glial heterotopia in an infant

Bilateral orbital glial heterotopia: A rare case report

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