Glass Ionomer Sealants Can Prevent Dental Caries but Cannot Prevent Posteruptive Breakdown on Molars Affected by Molar Incisor Hypomineralization: One-Year Results of a Randomized Clinical Trial

Abstract

To evaluate the preventive effect of glass ionomer cement (GIC) against dental caries and posteruptive breakdown (PEB) on molars affected by molar incisor hypomineralization (MIH). In this randomized clinical trial, 77 children aged 5–9 years with at least 1 MIH-affected molar and without PEB or dentin caries lesions (<i>n</i> = 228) were included and randomly allocated to one of the following groups: (1) MIH-affected molars that remained unsealed and (2) MIH-affected molars that received GIC sealants. Dental caries and PEB were clinically evaluated after 6 and 12 months. Associations between dental caries and PEB with independent variables were evaluated using logistic regression analysis (<i>p</i> < 0.05). The MIH-affected molars allocated to the GIC sealant group were less likely to develop dental caries compared to those allocated to the unsealed group (OR = 0.23; 95% CI 0.06–0.95). Conversely, application of a GIC sealant was not associated with prevention of PEB (<i>p</i> = 0.313). Furthermore, MIH-affected molars presenting yellow-brown opacities were almost 5 times more likely to develop dental caries (<i>p</i> = 0.013) and PEB (<i>p</i> = 0.001) compared to those presenting white-creamy opacities. We can conclude that GIC sealants can prevent dental caries on MIH-affected molars; however, the same protective effect was not observed for PEB.

A critical look at outcome measures: Comparison between four dental research journals by use of a hierarchical model

“…Clinical aspects of endodontic treatment in the International Endodontic Journal were addressed by radiographic healing combined with the presence or absence of clinical symptoms (Liu et al., 2021) or for example frequency of additional treatment (Markvart et al., 2021). In Caries Research , the clinical aspects were addressed by, for example, measuring the caries preventive effect of glass ionomer cement or the incidence of new non‐cavitated or number of cavitated lesions after fluoride varnish application (Schraverus et al., 2021; Turska‐Szybka et al., 2021). In the Journal of Clinical Periodontology , some clinical aspects of treatment were survival rate (Shi et al., 2020), smile attractiveness rated on VAS (Silva et al., 2021), root coverage aesthetic score (Zuhr et al., 2020), or tooth loss due to periodontitis (Ravidà et al., 2021).…”

Efficacy of Glass Ionomer Cement as Pit and Fissure Sealant in Permanent First Molars

“…Dental sealants have proven effective in preventing pit and fissure caries, with recent advancements in fluoride-containing sealants further enhancing their caries-preventive efficacy. Acid conditioning of the enamel prior to sealant application facilitates micromechanical retention of the coating [ 15 , 16 ]. Visual tactile assessment is commonly used to clinically evaluate pit and fissure sealant performance, categorizing sealants as intact, partially lost, or complete lost.…”

Protocolos clínicos em Hipomineralização Molar Incisivo (HMI): revisão integrativa da literatura

“…Eles mostram que a caseína fosfato de cálcio fosfopeptídeo amorfo (CFC-ACP) demonstrou ter um efeito remineralizador e dessensibilizante em dentes com HMI, pois produz uma solução supersaturada estável de cálcio e fosfato na superfície do esmalte. Em oposição, Schraverus et al (2021) afirmam que não há diferença significativa do efeito dessensibilizante do CFC ACP com ou sem flúor e que os dados disponíveis ainda são insuficientes para apoiar a aplicação de flúor para HMI. No entanto, relatam que os selantes de fissuras podem ter alguns benefícios para HMI leve em molares, pois auxiliam ainda mais na prevenção de lesões de cárie dental e quebra do esmalte.…”