Glandular neoplasms of the cervix

Waddell, Caroline C.; Chandra, Ashish

doi:10.1016/b978-0-7020-3154-0.00024-7

Cited by 5 publications

(8 citation statements)

References 151 publications

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“…Slides showing endocervical cells with changes in nuclear size, shape or staining that fall short of overt dyskaryosis 19 are regarded as ‘borderline nuclear change in endocervical cells’, and are currently included in NHSCSP code 8 14 . It is acknowledged that this category, which is similar to AGC, not otherwise specified, in TBS may be a separate group with a wider variety of underlying abnormalities than its squamous counterpart 20,21 …”

Section: Introductionmentioning

confidence: 99%

“…14 It is acknowledged that this category, which is similar to AGC, not otherwise specified, in TBS may be a separate group with a wider variety of underlying abnormalities than its squamous counterpart. 20,21 The cytological diagnosis and clinical management of women with glandular abnormalities present a problem for cytologists and colposcopists alike. The purpose of this study was, therefore, to review the risk of pre-invasive and invasive gynaecological pathology in women referred with ?glandular neoplasia on cervical cytology.…”

Section: Introductionmentioning

confidence: 99%

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Risk of significant gynaecological pathology in women with ?glandular neoplasia on cervical cytology

Talaat¹,

Brinkmann²,

Dhundee

et al. 2011

Cytopathology

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Risk of significant gynaecological pathology in women with ?glandular neoplasia on cervical cytology

Talaat¹,

Brinkmann²,

Dhundee

et al. 2011

Cytopathology

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“…This can lead to difficulty in identifying key nuclear and cytoplasmic features that could have otherwise made the interpretation more definitive, either toward benign/reactive or neoplastic. (Solomon, 2002;Chieng & Cangiarella, 2003;Waddell, 2003;Willson & Jones, 2004) .…”

Section: Atypical Glandular Cells (Agc)mentioning

confidence: 99%

Cytology of Cervical Intraepithelial Glandular Lesions

Ovanin-Rakić

Mahovlić²,

Audy-Jurković³

et al. 2012

Intraepithelial Neoplasia

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A B S T R A C T Cytological criteria for the identification of glandular intraepithelial lesions (GIL) have not yet been fully described, especially for the precursors of adenocarcinoma in situ (AIS), thus these lesions may frequently remain unrecognized. As most patients diagnosed with AIS or mild to moderate GIL (grades I, II) are free from clinical symptoms, cytology has a very responsible role in the detection of these lesions. The aim of the study was to achieve the most appropriate cytologic diagnosis of intraepithelial lesions of endocervical columnar epithelium, analyzing the cytology findings in patients with histologically verified AIS and GIL (I, II). The value of cytology in the detection and differential diagnosis was assessed in 123 patients with definitive histologic diagnosis of glandular lesions (AIS, n=13; GIL I, n=11; and GIL II, n=7) epithelium (95.7%; vs. 74.2%). The accuracy of cytology was higher in pure (AIS, 61.5% and GIL I, II, 22.2%) than in mixed lesions (25.9% and 20.6%). Continuous improvement in cervical specimens and cytodiagnostic skills, better understanding of intraepithelial adenocarcinoma and precursors, and their inclusion in the classification of cytologic and histologic findings are expected to upgrade the detection of these lesions, and to reduce the invasive cervical adenocarcinoma morbidity and mortality.

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“…The cytological identification of pre‐invasive lesions of endocervical origin hinges on the recognition of features attributable to high‐grade CGIN, formerly known as adenocarcinoma in situ (AIS). On primary screening, identification is very often made on the architectural features of cell groups and only then is individual cell morphology used to confirm the initial impression 20 …”

Section: ?Glandular Neoplasiamentioning

confidence: 99%

“…On primary screening, identification is very often made on the architectural features of cell groups and only then is individual cell morphology used to confirm the initial impression. 20 Although endocervical-type CGIN (Type I CGIN) is the most common and is associated with the most classic cytological appearances, less common subtypes (Type II CGIN) which include enteric and endometrioid lesions also need to be taken into account. On the whole, in conventional smears there is usually an abundance of neoplastic glandular material which may be appreciated on low power (·4) inspection.…”

Section: Nos (Uncertain Origin) Other (Ovarian or Metastatic Lesion Smentioning

confidence: 99%

The revised BSCC terminology for abnormal cervical cytology

et al. 2008

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The revised BSCC terminology for abnormal cervical cytologyThe BSCC terminology was originally published in 1986 and although highly successful, requires revision. Through a process of professional consensus and literature review this has been undertaken by the BSCC. The revision takes account of recent developments and improvements in understanding of morphology and disease process and is compatible with other terminologies in use elsewhere, whilst still maintaining a focus on practice in the UK cervical screening programmes.

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Glandular neoplasms of the cervix

Cited by 5 publications

References 151 publications

Risk of significant gynaecological pathology in women with ?glandular neoplasia on cervical cytology

Risk of significant gynaecological pathology in women with ?glandular neoplasia on cervical cytology

Cytology of Cervical Intraepithelial Glandular Lesions

The revised BSCC terminology for abnormal cervical cytology

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