Glandular cells in vaginal cytology Papanicolaou tests in patients with hysterectomy for endometrial adenocarcinoma

Abstract

The vaginal apex is the most common site of recurrence in patients with endometrial cancer. Although studies demonstrate that <1% of asymptomatic vaginal recurrences are detected by routine vaginal cytology alone, many practitioners still include it as part of the routine surveillance in these patients after hysterectomy. To further evaluate the effectiveness of vaginal cytology as a surveillance tool, we assessed the subsequent findings in patients reported to have benign and atypical glandular cells on vaginal cytology after hysterectomy performed for endometrial cancer.

Cytomorphologic clues for the diagnosis of fallopian tube prolapse in liquid‐based vault samples with review of the literature

“…Bland-looking glandular cells can be seen in post-hysterectomy vaginal samples due to vaginal adenosis, fallopian tubal prolapse, rectovaginal fistula, and metaplasia of squamous/atrophic vaginal lining epithelium. 12 FTP is seen as an infrequent complication following hysterectomy, whether vaginal, abdominal, or laparoscopic, especially when the fallopian tubes are fixed close to the apex of the vaginal vault. The exact incidence of the condition is not known, mainly due to under-reporting and misdiagnosis; however, it is believed to occur in around 1.3% of women post-hysterectomy.…”