Thirty-three paired accelerator mass spectrometry (AMS) radiocarbon dates on human and terrestrial faunal remains from the same Neolithic and Early Bronze Age graves are used to develop a correction for the freshwater reservoir effect (FRE) at Lake Baikal, Siberia. Excluding two outliers, stable nitrogen isotope (δ 15 N) values show a positive correlation (r 2 = 0.672, p < 0.000) with offsets in 14 C yr between paired human and fauna determinations. The highest offset observed in our data set is 622 yr, which is close to the value of ~700 yr suggested for endemic seals in the lake. For each per mil increase in δ 15 N, the offset increases by 77 ± 10 yr in the overall data set. However, there are indications that different regression models apply in each of two microregions of Cis-Baikal. In the first, sites on the southwest shore of the lake and along the Angara River show a strong positive correlation between δ 15 N values and offsets in 14 C yr (r 2 = 0.814, p < 0.000). In the other, the Little Sea, both δ 13 C and δ 15 N values make significant contributions to the model (adjusted r 2 = 0.878; δ 13 C p < 0.001; δ 15 N p < 0.000). This can be related to the complex 13 C ecology of the lake, which displays one of the widest ranges of δ 13 C values known for any natural ecosystem. The results will be important in terms of refining the culture-history of the region, as well as exploring the dynamic interactions of hunter-gatherer communities both synchronically and diachronically.