Giuseppe Prota (1938–2003)

d'Ischia, Marco

doi:10.1034/j.1600-0749.2003.00031.x

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Melanin Biosynthesis1

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2016

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“…The 5-S-glutathionyldopamine conjugate degrades to 5-cysteinyldopamine and reacts further to form neuromelanin. 10,11 Dopamine does not accumulate in the cytosol. It is degraded by monoamine oxidase or catechol-o-methyl transferase and further oxidized by aldehyde dehydrogenase using NAD + as electron acceptor, ultimately resulting in homovanillic acid.…”

Section: Melanin Biosynthesismentioning

confidence: 99%

Melanin from a physicochemical point of view

Menter

2016

Polymer International

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Melanin has an ambivalent nature; it can act as a protective or anti‐protective agent, depending on its previous history. In this article we briefly review the current state of understanding of melanin structure and biosynthesis, its binding with drugs and metals, its adsorption and (photo)semiconductive properties, and its ability to couple redox reactions There is now a greater appreciation of the structural and spectroscopic differences between 5,6‐dihydroxyindole and 5,6‐dihydroxyindole‐2‐carboxylic acid melanins and a greater knowledge of the kinetics of eumelanin to pheomelanin and neuromelanin transformations and the molecular links among them. The scope of drug and metal binding to melanin has expanded. Recent work has shown that melanin can act as an electronic–ionic conductor. Melanin can couple redox reactions for biologically and commercially relevant solid and gaseous systems. © 2016 Society of Chemical Industry

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Section: Melanin Biosynthesismentioning

confidence: 99%

Melanin from a physicochemical point of view

Menter

2016

Polymer International

View full text Add to dashboard Cite

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Giuseppe Prota (1938–2003)

Cited by 1 publication

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Melanin from a physicochemical point of view

Melanin from a physicochemical point of view

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