“…37 Although recruitment strategies have evolved over time, Zambian IP organizations initially met ambitious DREAMS enrollment targets without necessarily reaching the highest-risk AGYW through a schoolbased enrollment approach. While new evidence from Lesotho and Malawi indicate DREAMS may enhance psychosocial, financial, and other protective assets of these lower-risk AGYW, 42,43 substantial differences in sexual risk characteristics between DREAMS participants and unenrolled AGYW suggest convenience recruitment strategies, like school-based enrollment approaches, could attenuate potential effects of DREAMS on key indicators, like HIV incidence, reported in observational studies. 44,45 Innovative hotspotmapping approaches, like those used to identify where young women sell sex in Zimbabwe 40 and where AGYW meet male partners in Malawi, 46 are feasible strategies for venue enumeration and targeted recruitment of higher-risk AGYW.…”