Ginsenosides facilitate the anti-cancer efficacy of cyclophosphamide via modulating intestinal bacteria and alleviating intestinal mucositis in mammary carcinoma mice
Abstract:Background: Ginsenosides has been reported to facilitate the chemotherapy of cyclophosphamide (CTX), but the underlying mechanism is still elusive. Here, ICR mice bearing subcutaneous 4T1 tumor (mouse mammary carcinoma cells) were used to investigate the enhanced chemotherapeutic effects and underlying the mechanism of concurrent administration of ginsenosides and CTX. Results: Combinational treatment with ginsenosides in mice enhanced the anti-cancer efficacy of CTX as observed by elevated tumor growth inhibi… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.