Ginseng Radix et Rhizoma enhanced the effect of metoprolol in chronic heart failure by inhibiting autophagy in male C57BL/6J mice
Niu Zi-chang,
Han Xiao-ling,
Jin Qi
et al.
Abstract:Background
Ginseng Radix et Rhizoma (GS) is frequently used as an adjuvant therapy for patients with heart failure (HF). Metoprolol is widely used in patients with HF. However, there is no report on the combined effects of GS and metoprolol in patients with HF.
Objective
This study investigated the combined effects of GS and metoprolol in male C57BL/6J mice with HF and the underlying mechanisms.
Materials and methods
We utilized a mouse myocardial HF model to measure the serum levels of creatine kinase (CK… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.