Gingival crevicular fluid osteocalcin level as a biomarker for periodontitis stage III grade B and C response to periodontal treatment after 6 months follow up of Egyptian population sample- Controlled Clinical trial.
Abstract:Objectives: Periodontitis is characterized by an increased alveolar bone turnover with dominance of bone resorption over bone formation leading to alveolar bone loss and loss of attachment. Osteocalcin is the major noncollagenous calcium-binding single chain protein of bone and dentin matrix and it is a bone marker whose concentration in circulation has been used as a reflector of bone turnover.The present study was conducted to evaluate osteocalcin levels in healthy and diseased periodontium and to correlate … Show more
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