Gingival and bone tissue healing in lower third molar surgeries. Comparative study between use of platelet rich fibrin versus physiological healing

Castillo, Galo Fernando Guzmán; Miranda, Mayra Elizabeth Paltas; Bojorque, Juan Andrés Benenaula; Barragán, Katerine Isabel Núñez; García, Denisse Vanessa Simbaña

doi:10.1016/j.rodmex.2017.05.016

Cited by 5 publications

(15 citation statements)

References 14 publications

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“…Soft tissue healing was not heavily debated among authors and considered in the evaluations we analyzed, with 73% of the studies not assessing this factor. However, three authors focused their results specifically on this improvement, as was the case with Yelamali et al [16], Guzmán Castillo et al [19], and Revathy et al [25]. Measuring parameters like pain is subjective, while edema and trismus are assessed through measurements and consequently more concrete results are found.…”

Section: Total Articles 22mentioning

confidence: 99%

Como o uso de fibrina rica em plaquetas pode beneficiar as exodontias de terceiros molares mandibulares?

Lima,

Coutinho,

Viana

et al. 2024

Braz. Journ. Dentistry Oral Rad.

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Surgery for the removal of third molars is a surgical procedure commonly performed in Dentistry. It is associated with inflammatory events and possible complications, being more evident after the removal of lower molars, since in most cases there is a need for more invasive approaches. It is essential for the dentist to minimize such effects, providing a more peaceful postoperative period with less morbidity for the patient. In this context, platelet-rich fibrin (PRF) was developed, which is considered a platelet aggregate obtained by centrifugation of the patient's own blood and proposes to minimize inflammatory effects, accelerate healing and repair processes, and reduce postoperative complications. A literature review on the effect of L-PRF in sockets after the removal of mandibular third molars was conducted, evaluating its efficacy on pain, swelling, trismus, and healing. A bibliographic survey was performed on the PubMed, Web of Science, and Elsevier databases, using the following descriptors: 'platelet rich fibrin', 'third molar', and 'surgery', limiting to articles written in English published from 2013 to 2023. Thus, we have a current scientific overview of the real effect of using this platelet aggregate in the extraction of lower third molars. The studies reviewed, for the most part, showed positive results in improving pain, swelling, trismus, and healing.

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Section: Total Articles 22mentioning

confidence: 99%

Como o uso de fibrina rica em plaquetas pode beneficiar as exodontias de terceiros molares mandibulares?

Lima,

Coutinho,

Viana

et al. 2024

Braz. Journ. Dentistry Oral Rad.

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“…This review analyzed 17 parallel RCTs. Thirteen studies compared PRF treatment alone with physiological healing or blood clotting without additional treatment [1][2][3]5,13,14,17,19,20,22,[26][27][28][29][30]. One study included three groups and compared the use of PRF and PRF with mucosal flap with spontaneous healing [21].…”

Section: Description Of the Included Interventional Studiesmentioning

confidence: 99%

“…Patients were mainly studied with or without requiring dental exodontia (including the third molar) and/or implants were required for some but not all of the patients included in the studies [1,3,5,10,13,14,17,[19][20][21][22][26][27][28][29][30]. Additionally, some studies focused only on uniradicular teeth or premolars [2,10,21,26] (Table 3).…”

Section: Description Of the Included Interventional Studiesmentioning

confidence: 99%

“…Most studies did not report or specify the treated socket and/or ridge morphology. All studies reported the presence of 50% buccal and/or lingual bone walls [1,3,5,10,13,14,17,[19][20][21][22][26][27][28][29][30]. Most studies reported traumatic exodontia [1][2][3]5,10,13,17,[19][20][21][22][26][27][28][29][30]…”

Section: Description Of the Included Interventional Studiesmentioning

confidence: 99%

“…All studies reported the presence of 50% buccal and/or lingual bone walls [1,3,5,10,13,14,17,[19][20][21][22][26][27][28][29][30]. Most studies reported traumatic exodontia [1][2][3]5,10,13,17,[19][20][21][22][26][27][28][29][30]…”

Section: Description Of the Included Interventional Studiesmentioning

confidence: 99%

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Imaging Evaluation of Platelet-Rich Fibrin in Post-Exodontic Bone Regeneration: A Systematic Review

Molina-Barahona,

Delgado-Gaete,

Morales-Navarro

et al. 2023

Dentistry Journal

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Tooth extraction is the most common procedure in dental practice. However, in the long term, it may cause alveolar ridge atrophy. This systematic review aimed to evaluate the role of platelet-rich fibrin (PRF) in post-exodontic alveolar ridge preservation in terms of its effectiveness in the regeneration of bone tissue as assessed by imaging and its efficacy compared to physiological bone healing. The study is presented in accordance with the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. This systematic review was conducted using electronic databases such as PubMed, Scopus, Web of Science, and Science Direct. The gray literature search was conducted in the New York Academy of Medicine Grey Literature Report. All the studies in this systematic review were randomized controlled trials (RCTs). The risk of bias was performed according to the Cochrane Handbook for Systematic Reviews of Interventions 6.2 (RevMan 6.2). Considering the inclusion and exclusion criteria, we included 17 randomized clinical trials published up to 2022 investigating the efficacy of PRF in post-exodontic bone regeneration. Based on the results of clinical studies, it can be stated that despite not being statistically significant, PRF promotes neoformation and prevents bone loss between three and four months post-extraction.

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Evaluation of platelet-rich fibrin in post-exodontic bone regeneration: systematic review

Molina Barahona,

Navarro,

González Campoverde

et al. 2023

IJMBOA

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Objective: To analyze the use of platelet-rich fibrin in bone regeneration of postexodontic tooth sockets by means of a systematic review of updated randomized controlled clinical trials. Materials and methods: the present descriptive, documentary, cross-sectional study was carried out following PRISMA 2020 standards, a search of 25 scientific articles of randomized controlled clinical trials with a minimum of 8 patients who needed dental extractions was carried out, who were divided into two groups, one test group containing platelet-rich fibrin and the other control group without platelet-rich fibrin, articles were collected from databases such as Google Scholar, PubMed, Scielo, Redalyc, Embase, which were within the last 8 years, articles that did not meet the objectives that served for this study were excluded. Results: Of the 25 articles included in this systematic review, 15 were based on the extraction of bilateral impacted lower third molars, 8 on extractions of teeth due to endodontic failure and coronary fracture and 2 on the extraction of teeth prior to rehabilitation treatment with dental implants. Platelet-rich fibrin improves clinical and imaging conditions in post-exodontic patients, showing in the imaging evaluation after taking radiographs during the control weeks a better healing of soft tissues, a notable difference in bone filling and the formation of new bone. Conclusion: the use of platelet-rich fibrin is effective in the preservation of the alveolar ridge post-exodontia, maintaining vertical dimensional stability, beneficial also in cellular proliferation which improves bone loss, despite this there is no significant difference in the test sites treated with platelet-rich fibrin compared to control sites treated with physiological healing.

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Gingival and bone tissue healing in lower third molar surgeries. Comparative study between use of platelet rich fibrin versus physiological healing

Cited by 5 publications

References 14 publications

Como o uso de fibrina rica em plaquetas pode beneficiar as exodontias de terceiros molares mandibulares?

Como o uso de fibrina rica em plaquetas pode beneficiar as exodontias de terceiros molares mandibulares?

Imaging Evaluation of Platelet-Rich Fibrin in Post-Exodontic Bone Regeneration: A Systematic Review

Evaluation of platelet-rich fibrin in post-exodontic bone regeneration: systematic review

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