Ginger Bioactives: A Comprehensive Review of Health Benefits and Potential Food Applications
Muhammad Nouman Shaukat,
Akmal Nazir,
Biagio Fallico
Abstract:Ginger is an herbaceous and flowering plant renowned for its rhizome, which is widely employed as both a spice and an herb. Since ancient times, ginger has been consumed in folk medicine and traditional cuisines for its favorable health effects. Different in vitro and in vivo studies have disclosed the advantageous physiological aspects of ginger, primarily due to its antioxidant, anti-inflammatory, antimicrobial, and anti-carcinogenic properties. These health-promoting features are linked to the variety of bi… Show more
“…Ginger includes both volatiles such as geraniol, borneol, terpineol, curcumene, zingiberol, α-farnesene, α-sesquiphellandrene, α- β-bisabolene, β-elemene etc., as well as non-volatile compounds such as gingerols, shogaols, zingerone, and paradols [ 7 ]. The composition of ginger extracts and oils differ significantly.…”
Section: Resultsmentioning
confidence: 99%
“…In general, it is well reported in the literature that the components of ginger extracts/essential oils have significant bioactivities and health-promoting properties, and thus can have applications in various sectors [ 7 , 8 , 9 , 10 , 11 ]. Based on literature data, ginger extracts/oils containing most of the bioactive compounds found in the present have been reported to have significant pharmacological, medicinal, and cosmetic applications, as they have been found to possess antimicrobial and antiseptic activity, anti-carcinogenic potential, neuroprotective activity, anti-obese activity, anti-diabetic effect, and analgesic activity as well as provide cardiovascular protection [ 8 , 11 ].…”
Section: Resultsmentioning
confidence: 99%
“…Based on literature data, ginger extracts/oils containing most of the bioactive compounds found in the present have been reported to have significant pharmacological, medicinal, and cosmetic applications, as they have been found to possess antimicrobial and antiseptic activity, anti-carcinogenic potential, neuroprotective activity, anti-obese activity, anti-diabetic effect, and analgesic activity as well as provide cardiovascular protection [ 8 , 11 ]. Another significant application is in the food industry, as the bioactive compounds of ginger can provide oxidative and storage stability, sensorial properties, preservation, oxidative resistance, and anti-bacterial activity in consuming products [ 7 ]. As well, another notable factor is its application in agriculture for the control of plant diseases which minimizes simultaneously the possible negative effects on the environment, animals, and human health [ 9 , 10 ].…”
Section: Resultsmentioning
confidence: 99%
“…Moreover, polysaccharides have also been reported to be components of ginger extracts [ 1 ]. The bioactive compounds present in ginger extracts/oils lead to a vast number of applications in the medicinal and cosmetic sector, as well as the food industry and the agriculture sector [ 7 , 8 , 9 , 10 , 11 ].…”
Zingiber officinale Roscoe (ginger) is a plant from the Zingiberaceae family, and its extracts have been found to contain several compounds with beneficial bioactivities. Nowadays, the use of environmentally friendly and sustainable extraction methods has attracted considerable interest. The main objective of this study was to evaluate subcritical propane (scPropane), supercritical CO2 (scCO2), and supercritical CO2 with ethanol (scCO2 + EtOH) as co-solvent methods for the extraction of high value products from ginger. In addition, the reuse/recycling of the secondary biomass in a second extraction as a part of the circular economy was evaluated. Both the primary and the secondary biomass led to high yield percentages, ranging from 1.23% to 6.42%. The highest yield was observed in the scCO2 + EtOH, with biomass prior used to scCO2 extraction. All extracts presented with high similarities as far as their total phenolic contents, antioxidant capacity, and chemical composition. The most abundant compounds, identified by the two different gas chromatography-mass spectrometry (GC-MS) systems present, were a-zingiberene, β- sesquiphellandrene, a-farnesene, β-bisabolene, zingerone, gingerol, a-curcumene, and γ-muurolene. Interestingly, the reuse/recycling of the secondary biomass was found to be promising, as the extracts showed high antioxidant capacity and consisted of significant amounts of compounds with beneficial properties.
“…Ginger includes both volatiles such as geraniol, borneol, terpineol, curcumene, zingiberol, α-farnesene, α-sesquiphellandrene, α- β-bisabolene, β-elemene etc., as well as non-volatile compounds such as gingerols, shogaols, zingerone, and paradols [ 7 ]. The composition of ginger extracts and oils differ significantly.…”
Section: Resultsmentioning
confidence: 99%
“…In general, it is well reported in the literature that the components of ginger extracts/essential oils have significant bioactivities and health-promoting properties, and thus can have applications in various sectors [ 7 , 8 , 9 , 10 , 11 ]. Based on literature data, ginger extracts/oils containing most of the bioactive compounds found in the present have been reported to have significant pharmacological, medicinal, and cosmetic applications, as they have been found to possess antimicrobial and antiseptic activity, anti-carcinogenic potential, neuroprotective activity, anti-obese activity, anti-diabetic effect, and analgesic activity as well as provide cardiovascular protection [ 8 , 11 ].…”
Section: Resultsmentioning
confidence: 99%
“…Based on literature data, ginger extracts/oils containing most of the bioactive compounds found in the present have been reported to have significant pharmacological, medicinal, and cosmetic applications, as they have been found to possess antimicrobial and antiseptic activity, anti-carcinogenic potential, neuroprotective activity, anti-obese activity, anti-diabetic effect, and analgesic activity as well as provide cardiovascular protection [ 8 , 11 ]. Another significant application is in the food industry, as the bioactive compounds of ginger can provide oxidative and storage stability, sensorial properties, preservation, oxidative resistance, and anti-bacterial activity in consuming products [ 7 ]. As well, another notable factor is its application in agriculture for the control of plant diseases which minimizes simultaneously the possible negative effects on the environment, animals, and human health [ 9 , 10 ].…”
Section: Resultsmentioning
confidence: 99%
“…Moreover, polysaccharides have also been reported to be components of ginger extracts [ 1 ]. The bioactive compounds present in ginger extracts/oils lead to a vast number of applications in the medicinal and cosmetic sector, as well as the food industry and the agriculture sector [ 7 , 8 , 9 , 10 , 11 ].…”
Zingiber officinale Roscoe (ginger) is a plant from the Zingiberaceae family, and its extracts have been found to contain several compounds with beneficial bioactivities. Nowadays, the use of environmentally friendly and sustainable extraction methods has attracted considerable interest. The main objective of this study was to evaluate subcritical propane (scPropane), supercritical CO2 (scCO2), and supercritical CO2 with ethanol (scCO2 + EtOH) as co-solvent methods for the extraction of high value products from ginger. In addition, the reuse/recycling of the secondary biomass in a second extraction as a part of the circular economy was evaluated. Both the primary and the secondary biomass led to high yield percentages, ranging from 1.23% to 6.42%. The highest yield was observed in the scCO2 + EtOH, with biomass prior used to scCO2 extraction. All extracts presented with high similarities as far as their total phenolic contents, antioxidant capacity, and chemical composition. The most abundant compounds, identified by the two different gas chromatography-mass spectrometry (GC-MS) systems present, were a-zingiberene, β- sesquiphellandrene, a-farnesene, β-bisabolene, zingerone, gingerol, a-curcumene, and γ-muurolene. Interestingly, the reuse/recycling of the secondary biomass was found to be promising, as the extracts showed high antioxidant capacity and consisted of significant amounts of compounds with beneficial properties.
“…Manfaat nutrisi dan nutrasetikal yang dimiliki jahe berkaitan dengan senyawa bioaktif yang dikandungnya. Jahe mengandung komponen volatil berupa minyak esensial (geraniol, borneol, terpineol, zingiberenol, sineol, limonen, camphene, curcumene, zingiberol, geranil asetat, linalool, α-Farnesene, α-sesquifelandren, α-zingiberen, β-bisabolen, β-elemen, and β-felandren), komponen non-volatil seperti oleoresin (gingerol, shogaol, zingeron dan paradol), komponen organik dan anorganik (Nair, 2020;Shaukat et al, 2023).…”
Nutrasetikal merupakan pangan atau bagian dari pangan yang memberikan manfaat medis atau kesehatan, meliputi pencegahan dan terapi suatu penyakit. Jahe (Zingiber officinale Roscoe) merupakan salah satu tumbuhan perenial yang banyak dijumpai di Indonesia dan dapat diolah menjadi nutrasetikal yang bermanfaat bagi kesehatan seperti wedang ronde. Melalui kegiatan pengabdian kepada masyarakat ini ibu-ibu PKK Desa Gegerung, Kecamatan Lingsar, Lombok Barat, Nusa Tenggara Barat diberikan edukasi dan pelatihan pembuatan nutrasetikal wedang ronde. Tahapan pada kegiatan ini meliputi persiapan kegiatan, pelaksanaan sosialisasi, pelatihan pembuatan nutrasetikal dengan metode partisipatif dan evaluasi kegiatan melalui pemberian umpan balik oleh peserta. Melalui kegiatan ini, pengetahuan terhadap nutrasetikal meningkat dan peserta mendapatkan kemampuan di dalam pembuatan wedang ronde. Berdasarkan hasil kuesioner juga diketahui bahwa 94% peserta merasa kegiatan ini dirasa sangat baik dan sangat bermanfaat. Peserta juga merasa dapat mengaplikasikan ilmu yang didapat setelah pelatihan ini. Nutraceuticals are foods or parts of food that provide medical or health benefits, including prevention and therapy of disease. Ginger (Zingiber officinale Roscoe) is a perennial plant that is often found in Indonesia and can be processed into nutraceuticals that are beneficial for health such as wedang ronde. Through this community service activity, PKK women in Gegerung Village, Lingsar District, West Lombok, West Nusa Tenggara were given education and training in making the nutraceutical wedang ronde. The stages in this activity include activity preparation, implementation of socialization, training in making nutraceuticals using participatory methods and evaluation of activities through providing feedback by participants. Through this activity, participant’s knowledge of nutraceuticals increased and participants gained skills in making wedang ronde. Based on the results of the questionnaire, it was also known that 94% of participants felt that this activity was very good and very useful. Participants also felt they could apply the knowledge gained after this training
Colorectal cancer (CRC) is the fourth most common cause of malignant tumor death. The development of novel, more effective drugs is desperately needed to treat CRC. Zingiber officinale is believed to possess anticancer properties due to its flavonoids and phenols. Using Soxhlet (SOXT) and maceration (MACR) techniques, the present study aimed to evaluate the amounts of quercetin, gallic acid, rutin, naringin, and caffeic acid in ginger capsules of Z. officinale. High‐performance liquid chromatography (HPLC)/ultraviolet was used for separation and quantitation. In vitro toxicity evaluation of ginger capsules on the CRC cell line HT‐29 was also conducted to assess the anticancer activity of the supplement. The cell line HT‐29 (HTB‐38) colorectal adenocarcinoma was utilized for the antiproliferative effect of 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyl tetrazolium bromide. Ginger herbal supplement extract at dosages of 200 and 100 μg had strong cytotoxic effects (IC50 < 50 μg/mL) on HT‐29 CRC cells via MACR. This extract is comparable to the SOXT extract, which has an IC50 of less than 50 μg/mL. The anticancer effect of ginger herbal supplement formulations against CRC lines was investigated, and the results obtained from both the MACR and SOXT extraction procedures were noteworthy. The quercetin content was the highest of all the extracts according to the HPLC data.
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