Gigantiform cementoma of the mandible: case report and literature review

Abstract

The gigantiform cementoma (GC) is an extremely rare, benign condition of fibro-cemento-osseous origin that is noted in the jaws, more commonly in younger individuals. Both sporadic cases of GC and those with an autosomal dominant pattern of inheritance have been reported in the English literature. There exists a great deal of overlap and confusion between GC and other benign, reactive or neoplastic fibro-osseous lesions, especially florid cement-osseous dysplasia and ossifying fibroma. The GC typically presents as a multiquadrant, expansile, mixed radiolucent-opaque lesions that frequently cross the midline of the jaws. We report a case of GC in a 41-year-old Haitian female. Clinical, radiographic, and microscopic features of this condition are presented, along with criteria to differentiate GC from other fibro-osseous diseases of the jaws. A brief review of the literature with clinical, radiographic findings and treatment recommendation is discussed. Additional cases of GC, as well as further investigation of the genes that may be involved, are needed to further understand this rare entity.

Características clínicas e imagenológicas del cementoma gigantiforme familiar. Una revisión de la literatura

“…Histológicamente, el CGF es descrito como fibromas cemento osificantes de hueso inmaduro y masas calcificadas, que pueden tener una composición variada de tejido fibroso y calcificado 14 . En un reporte de caso, se demostró que la toma de la muestra para la biopsia no es fácil, al ser una lesión de consistencia dura y hemorrágica, por lo tanto, no se puede separar del hueso de manera sencilla 21 .…”