Gibberellin biosynthesis and metabolism: A convergent route for plants, fungi and bacteria

Salazar-Cerezo, Sonia; Martínez-Montiel, Nancy; García-Sánchez, Jenny; Pérez-y-Terrón, Rocío; Martínez-Contreras, Rebeca D.

doi:10.1016/j.micres.2018.01.010

Cited by 163 publications

(93 citation statements)

References 157 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Durante este estudio se pudo observar que estas sustancias tenían la capacidad de iniciar y sustentar la proliferación de tejidos madre cuando eran aplicadas sobre organismos vegetales en pequeñas cantidades (15). Con el paso del tiempo fueron estudiándose otros tipos de sustancias que podían tener un efecto similar, encontrando en el agua de coco una de las primeras citoquininas que fue aislada y reconocida por primera vez como la zeatina (proveniente del endospermo inmaduro del maíz) (16,17).…”

Section: Citoquininasunclassified

“…Su efecto en el sistema vegetal casi siempre suele acompañarse de la presencia de auxinas debido a su alta complementariedad en la estimulación del crecimiento y desarrollo vegetal, por lo que una concentración similar de la relación auxinas-citoquininas puede inducir la proliferación de células no diferenciadas (meristemos o callos vegetales), mientras que una mayor concentración de auxinas podría generar un incremento en la producción de raíces, una concentración mayor de citoquininas puede inducir una mayor producción de brotes vegetales (yemaciones), lo cual puede sugerir que una concentración ideal de ambas fitohormonas en un medio de cultivo estable o en un sustrato adecuado podrían mejorar y acelerar el crecimiento vegetal (16,19,20).…”

Section: Citoquininasunclassified

See 1 more Smart Citation

Principales reguladores hormonales y sus interacciones en el crecimiento vegetal

Cortes

Godoy²,

Cortés³

et al. 2019

nova

View full text Add to dashboard Cite

Una hormona vegetal o fitohormona es un compuesto producido internamente por una planta, que ejerce su función en muy bajas concentraciones y cuyo principal efecto se produce a nivel celular, cambiando los patrones de crecimiento de los vegetales y permitiendo su control. Los reguladores vegetales son compuestos sintetizados químicamente u obtenidos de otros organismos y son, en general, mucho más potentes que los análogos naturales. Es necesario tener en cuenta aspectos críticos como oportunidad de aplicación, dosis, sensibilidad de la variedad, condición de la planta, etc., ya que cada planta requerirá de unas condiciones específicas de crecimiento que pueden afectarse por la concentración de ellos en el medio. Los reguladores vegetales son productos sintéticos que se han convertido en las primeras herramientas capaces de controlar el crecimiento y actividad bioquímica de las plantas por lo que su uso ha aumentado en los últimos años. Esta revisión busca hacer una recopilación bibliográfica de los primeros acontecimientos de la aplicación de los reguladores de crecimiento vegetal. Se presentan las principales características fisiológicas que pueden desarrollar la aplicación de estos sobre el crecimiento vegetal a nivel celular y su repercusión a nivel fenotípico; además, se describen las principales fitohormonas más conocidas en la aplicación biotecnológica. Entre ellas se encuentran auxinas, giberelinas, citoquininas, ácido abscísico, ácido salicílico, poliaminas, jasmonatos y derivados, brasinoesteroides, etileno y estrigolactonas. Se detallan las principales funciones a nivel del metabolismo vegetal y sus posibles interacciones intra e intercelular.

show abstract

Section: Citoquininasunclassified

Principales reguladores hormonales y sus interacciones en el crecimiento vegetal

Cortes

Godoy²,

Cortés³

et al. 2019

nova

View full text Add to dashboard Cite

show abstract

“…Phylogenetic analysis also revealed distinct differences between the two species, such as the number of each subfamily. In some studies, there was another subfamily in some species, GA7ox [29,30]. GA7ox, which oxidizes GA 12 -aldehyde to GA 12 and possesses mono-oxygenase 7-oxidase activity, was reported in pumpkin and cucumber but has not been found in other species.…”

Section: Gaoxes Display Both Conserved and Diverse Characters In Plantsmentioning

confidence: 99%

Genome-wide analysis of gibberellin-dioxygenases genes in rice

Liu¹,

Huang²,

Xu³

et al. 2019

Preprint

View full text Add to dashboard Cite

Background Gibberellins (GAs), a pivotal plant hormone, play fundamental roles in plant development and growth. In rice, gibberellin-dioxygenases (GAoxes), OsGA20ox, OsGA3ox and OsGA2ox, are involved in the biosynthesis and deactivation of gibberellins. However, a comprehensive genome-wide analysis of gibberellin-dioxygenases genes is still uncovered.Results In this study, a total of 95 candidate OsGAox genes were found and 19 OsGAox genes were further analyzed. Results of phylogenetic tree showed that the OsGAox genes in Arabidopsis and rice were divided into four subgroups and shared some common features. Furthermore, analysis of gene structure and conserved motifs revealed that splicing phase and motifs were well conserved during the evolution of GAox genes in Arabidopsis and rice, and some specific motifs still need to be further studied. Exploration of expression profiles indicated that most of OsGAox genes exhibited tissue-specific expression patterns, implied their complicated functions. Moreover, the expression patterns of these genes under GA 3 and PAC treatment were investigated, and result showed that some genes, OsGA2ox3, OsGA2ox5, OsGA2ox7, OsGA2ox9, OsGA20ox2, and OsGA20ox4, may play a major role in GA homeostasis to cope with exogenous GA.Conclusions Our study provided a comprehensive analysis of the OsGAox gene family. Splicing characteristics and conserved motifs indicated the evolutionary conserved function in plants. Expression profiles indicated that each OsGAox gene has complicated and special functions. Although plenty of GAoxes were involved in the endogenous GA metabolism, only some of them acted in response to the exogenous GA treatment, which provided available information for researchers to manipulate the chemical GAs to improve the plant architecture and production.

show abstract

“…In plants, diterpenes play diverse roles such as protection against pathogens and herbivores [9] and production of growth regulators such as gibberellins [10][11][12]. Plants, fungi and bacteria produce gibberellins from a universal precursor, ent-kaurene, which may be synthesized from GGPP in a single step or in two steps, via the intermediate ent-copalyl diphosphate (CDP) [13]. Gibberellins are used as a sustainable means of increasing yields and stress-tolerance in agriculture and floriculture but are currently expensive, leading to calls for biotechnological approaches to reduce cost and to increase the diversity of commercially available gibberellins [13,14].…”

mentioning

confidence: 99%

“…Plants, fungi and bacteria produce gibberellins from a universal precursor, ent-kaurene, which may be synthesized from GGPP in a single step or in two steps, via the intermediate ent-copalyl diphosphate (CDP) [13]. Gibberellins are used as a sustainable means of increasing yields and stress-tolerance in agriculture and floriculture but are currently expensive, leading to calls for biotechnological approaches to reduce cost and to increase the diversity of commercially available gibberellins [13,14]. Besides serving as the precursor to gibberellins, ent-kaurene may also be transformed into a variety of bioactive derivatives, with a range of potential applications.…”

mentioning

confidence: 99%

Production of ent-kaurene from lignocellulosic hydrolysate in Rhodosporidium toruloides

et al. 2020

View full text Add to dashboard Cite

Background: Rhodosporidium toruloides has emerged as a promising host for the production of bioproducts from lignocellulose, in part due to its ability to grow on lignocellulosic feedstocks, tolerate growth inhibitors, and co-utilize sugars and lignin-derived monomers. Ent-kaurene derivatives have a diverse range of potential applications from therapeutics to novel resin-based materials. Results: The Design, Build, Test, and Learn (DBTL) approach was employed to engineer production of the non-native diterpene ent-kaurene in R. toruloides. Following expression of kaurene synthase (KS) in R. toruloides in the first DBTL cycle, a key limitation appeared to be the availability of the diterpene precursor, geranylgeranyl diphosphate (GGPP). Further DBTL cycles were carried out to select an optimal GGPP synthase and to balance its expression with KS, requiring two of the strongest promoters in R. toruloides, ANT (adenine nucleotide translocase) and TEF1 (translational elongation factor 1) to drive expression of the KS from Gibberella fujikuroi and a mutant version of an FPP synthase from Gallus gallus that produces GGPP. Scale-up of cultivation in a 2 L bioreactor using a corn stover hydrolysate resulted in an ent-kaurene titer of 1.4 g/L. Conclusion: This study builds upon previous work demonstrating the potential of R. toruloides as a robust and versatile host for the production of both mono-and sesquiterpenes, and is the first demonstration of the production of a non-native diterpene in this organism.

show abstract

Gibberellin biosynthesis and metabolism: A convergent route for plants, fungi and bacteria

Cited by 163 publications

References 157 publications

Principales reguladores hormonales y sus interacciones en el crecimiento vegetal

Principales reguladores hormonales y sus interacciones en el crecimiento vegetal

Genome-wide analysis of gibberellin-dioxygenases genes in rice

Production of ent-kaurene from lignocellulosic hydrolysate in Rhodosporidium toruloides

Contact Info

Product

Resources

About