Giardia VSPAS7 protein attenuates Giardia intestinalis-induced host macrophage pyroptosis
Min Sun,
Zhiteng Zhao,
Ying Li
et al.
Abstract:Background
The unicellular protozoan parasite Giardia intestinalis, which primarily infects humans and animals such as cattle and sheep, is having a major negative impact on public health. Giardia is able to evade the recognition and elimination of the host immune system because of the trophozoite surface and extracellular vesicles (EVs) covered by variant-specific surface proteins (VSPs). As key proteins for immune evasion, whether VSPs can regulate Giardia-induced pyroptosis and promote Giard… Show more
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