Giardia duodenalis

Rojas-López, Laura; Marques, Rafael C.; Svärd, Staffan G.

doi:10.1016/j.pt.2022.01.001

Cited by 12 publications

(9 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The life cycle of G. duodenalis comprises rapidly multiplying trophozoites and environmentally hardy cysts that are released in the feces and spread through the fecal-oral route [ 15 ]. The trophozoite is the vegetative form and replicates in the small intestine of the host, and the cyst is the environmentally stable stage of the parasite life cycle that facilitates the zoonotic transmission of cysts passed in the feces of one host into the environment to be ingested by the subsequent host, leading to waterborne or foodborne outbreaks [ [16] , [17] , [18] , [19] ].…”

Section: Introductionmentioning

confidence: 99%

Role of rodents in the zoonotic transmission of giardiasis

Qin

et al. 2023

One Health

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

Role of rodents in the zoonotic transmission of giardiasis

Qin

et al. 2023

One Health

View full text Add to dashboard Cite

“…Te G. duodenalis life cycle comprises rapidly multiplying trophozoites and environmentally hardy cysts, which are released in the feces and spread via the fecal-oral route [5]. While the cysts cannot be distinguished morphologically, molecular biological analysis revealed that G. duodenalis isolates are genotypically divided into eight genetic assemblages designated A through H, where each assemblage has a distinct host range [6].…”

Section: Introductionmentioning

confidence: 99%

Potential Zoonotic Transmission of Giardia duodenalis between Children and Calves in Bangladesh

Karim

Siddiki

et al. 2023

Transboundary and Emerging Diseases

View full text Add to dashboard Cite

Giardia duodenalis is a zoonotic protozoan parasite that causes gastrointestinal illness in humans and livestock. We studied the genetic diversity of G. duodenalis in children and calves from Bangladesh to determine its zoonotic potential. Fecal samples collected from children (299) and calves (699) were screened with nested PCR with primers targeting the ssu rRNA gene for G. duodenalis. Positive samples were further multilocus genotyped using the β-giardin (bg), glutamate dehydrogenase (gdh), and triose phosphate isomerase (tpi) genes. The overall infection rate of G. duodenalis was 21.1% (63/299) in children and 5.7% (40/699) in calves. There were no significant differences in infection with G. duodenalis among age groups, sex, and study areas in children and calves. Multilocus genotyping (MLG) of human G. duodenalis identified zoonotic assemblages A (34.0%, 18/53) and B (50.9%, 27/53) and a so-called ruminant-specific assemblage E (11.3%, 6/53), as well as two mixed assemblages, B/D (1/53) and B/E (1/53). Assemblage E predominated in calves (82.3%, 28/34), followed by assemblages A (11.8%, 4/34) and B (5.9%, 2/34). Overall, zoonotic assemblages A, B, and E were found in 6.0% (18/299), 9.0% (27/299), and 2.0% (6/299) of the children’s stool samples, respectively, and 0.6% (4/699), 0.3% (2/699), and 4.0% (28/699) of the calf fecal samples, respectively. Although there was a difference in the distribution of subassemblages in humans (mostly AII) and calves (mostly AI), the zoonotic assemblages A, B, and E present in both children and calves suggest the potential for zoonotic transmission of G. duodenalis. This molecular study highlights the fact that G. duodenalis infections were common in the study areas, with potential zoonotic transmission between children and calves, implying that cattle might play a role in G. duodenalis zoonotic transmission.

show abstract

“…G. duodenalis life cycle consists of two stages: rapidly multiplying trophozoites and environmentally hardy cysts [ 8 ]. Trophozoites are the vegetative form of G. duodenalis that replicates in the host's small intestine.…”

Section: Introductionmentioning

confidence: 99%